Abstract View

Author(s): Ankit Yadav1, Neeraj kumar2, Abhishek Kumar3, Chetan4, Ajay kumar Garg.5

Email(s): 1ajay.pharma3006@gmail.com

Address:

    School of Pharmacy, Raffles University, Neemrana Behror - Kotputli, Rajasthan-301705.

Published In:   Volume - 3,      Issue - 3,     Year - 2024

DOI: Not Available

 View HTML        View PDF

Please allow Pop-Up for this website to view PDF file.

ABSTRACT:
Diabetes is a silent killer that causes significant economic loss, particularly in poor countries like India. Improved treatments with minimal side effects are necessary to reduce the impact on individual and societal health and economics. The study aimed to develop a polyherbal powder for diabetes mellitus and assess its organoleptic, rheological, physicochemical, and phytochemical properties. The polyherbal powder was made with herbs including Ocimum sanctum, Aegle marmelos, Emblica officinalis, Trigonella foenum-graecum, Terminalia bellirica, Terminalia chebula, Momordica charantia, Syzgium cumini, Cinnamomum zeylanicum, and Curcuma longa. The evaluations followed conventional methods. The polyherbal powder's organoleptic properties revealed a dull brown colour, Characteristic aroma and astringent flavour, with a somewhat fine texture. Qualitative phytochemical study identified flavonoids, alkaloids, terpenoids, tannins, steroids, carbohydrates, and glycosides. Physicochemical investigation showed that the polyherbal powder was stable and flowed smoothly. The polyherbal powder was investigated for its ability to cure diabetes mellitus.

Cite this article:
Ankit Yadav, Neeraj kumar, Abhishek Kumar, Chetan, Ajay kumar Garg. Phytochemical and Physical Powder Characteristic Evaluation of Poly Herbal Formulation. IJRPAS, May-June 2024; 3(3): 186-199.


[1]      R. Unnikrishnan, R. M. Anjana, and V. Mohan, “Diabetes mellitus and its complications in India,” Nat. Rev. Endocrinol., vol. 12, no. 6, pp. 357–370, 2016, doi: 10.1038/nrendo.2016.53.

[2]      T. Nagja, K. Vimal, and A. Sanjeev, “Anti-diabetic activity of a polyherbal formulation in streptozotocin induced type 2 diabetic rats,” J. Nat. Remedies, vol. 16, no. 4, pp. 148–152, 2016, doi: 10.18311/jnr/2016/15323.

[3]      R. A. Antora and R. M. Salleh, “Antihyperglycemic effect of Ocimum plants: A short review,” Asian Pac. J. Trop. Biomed., vol. 7, no. 8, pp. 755–759, 2017, doi: 10.1016/j.apjtb.2017.07.010.

[4]      P. PrabhuT and C. AtleeW, “Anti-inflammatory, anti arthritis and analgesic effect of ethanolic extract of whole plant of Merremia Emarginata Burm.F,” Cent. Eur. J. Exp. Biol., vol. 1, no. 3, pp. 94–99, 2012, [Online]. Available: http://scholarsresearchlibrary.com/archive.html

[5]      Thillaivanan S, “Challenges, Constraints and Opportunities in Herbal Medicines-A Review,” Int. J. Herb. Med., vol. 2, no. 1, pp. 21–24, 2014, [Online]. Available: http://scholarsresearchlibrary.com/archive.html

[6]      C. C. Falzon and A. Balabanova, “Phytotherapy: An Introduction to Herbal Medicine,” Prim. Care - Clin. Off. Pract., vol. 44, no. 2, pp. 217–227, 2017, doi: 10.1016/j.pop.2017.02.001.

[7]      P. Bhattacharyya and A. Bishayee, “Ocimum sanctum Linn. (Tulsi): An ethnomedicinal plant for the prevention and treatment of cancer,” Anticancer. Drugs, vol. 24, no. 7, pp. 659–666, 2013, doi: 10.1097/CAD.0b013e328361aca1.

[8]      L. I. G. Paula-Freire, G. R. Molska, M. L. Andersen, and E. L. D. A. Carlini, “Ocimum gratissimum Essential Oil and Its Isolated Compounds (Eugenol and Myrcene) Reduce Neuropathic Pain in Mice,” Planta Med., vol. 82, no. 3, pp. 211–216, 2015, doi: 10.1055/s-0035-1558165.

[9]      S. Dasaroju and K. M. Gottumukkala, “Review Article Current Trends in the Research of,” Int.J.Phara.Sci.Rev.Res, vol. 24, no. 2, pp. 150–159, 2014.

[10]    A. Ansari et al., “Emblica officinalis improves glycemic status and oxidative stress in STZ induced type 2 diabetic model rats,” Asian Pac. J. Trop. Med., vol. 7, no. 1, pp. 21–25, 2014, doi: 10.1016/S1995-7645(13)60185-6.

[11]    Gaber E. El-Desoky, “Antidiabetic and hypolipidemic effects of Ceylon cinnamon (Cinnamomum verum) in alloxan-diabetic rats,” J. Med. Plants Res., vol. 6, no. 9, pp. 1685–1691, 2012, doi: 10.5897/jmpr11.1472.

[12]    T. Nisar, M. Iqbal, A. Raza, M. Safdar, F. Iftikhar, and M. Waheed, “Turmeric: A Promising Spice for Phytochemical and Antimicrobial Activities,” J. Agric. Environ. Sci, vol. 15, no. 7, pp. 1278–1288, 2015, doi: 10.5829/idosi.aejaes.2015.15.7.9528.

[13]    V. B. Gawali, M. Bhalsingh, N. B. Dalvi, and Y. S. Tarkasband, “Development and evaluation of polyhebral powder formulation as energy booster,” J. Pharmacogn. Phytochem., vol. 7, no. 3, pp. 1576–1580, 2018.

[14]    A. I. Hussain, F. Anwar, P. S. Nigam, M. Ashraf, and A. H. Gilani, “Seasonal variation in content, chemical composition and antimicrobial and cytotoxic activities of essential oils from four mentha species,” J. Sci. Food Agric., vol. 90, no. 11, pp. 1827–1836, 2010, doi: 10.1002/jsfa.4021.

[15]    H. S. Chandel, A. K. Pathak, and M. Tailang, “Standardization of some herbal antidiabetic drugs in polyherbal formulation,” Pharmacognosy Res., vol. 3, no. 1, pp. 49–56, 2011, doi: 10.4103/0974-8490.79116.

[16]    M. S. Baliga et al., “Ocimum Sanctum L (Holy Basil or Tulsi) and its phytochemicals in the prevention and treatment of cancer,” Nutr. Cancer, vol. 65, no. SUPPL.1, pp. 26–35, 2013, doi: 10.1080/01635581.2013.785010.

 

Related Images:



Recent Images



Phytosomes: Lipid-Based Nanocarriers for Enhanced Herbal Bioavailability
A Review on Nanosponges: Versatile Carriers for Enhanced Drug Delivery
Risk-Based Matrix Approach for Determining Effort, Formality, and Documentation in Cleaning Validation
Transformation of Traditional Bajrang Lep into a Modern Polyherbal Hydrogel: Formulation and Evaluation of a Topical Anti-inflammatory Preparation
Clinical and Observational Study on Sickle Cell Disease in Akkalkuwa Region, Maharashtra
Understanding Drug Development Failures: Scientific, Financial, and Regulatory Drivers
Pluronic-Lecithin Organogels as A Novel Carrier for Dermal Delivery: A Review
Synergistic Therapeutic Potential of Elaeocarpus ganitrus and Withania somnifera in Epilepsy Management: A Comprehensive Review
Comprehensive Review of Co-Processing Technology in Pharmaceuticals
Investigation and Effective CAPA System:  The Biggest Opportunities of the Investigation CAPA System & How to Fix Them

Tags