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Author(s): Shaikh Samrin Mohammad Tufail*1, Kashtriya Jayshri Prakash2, Kazi Shifa Abdul Wadood.3

Email(s): 1samrinshaikh51221@gmail.com

Address:

    JIIU’s Ali- Allana College Pharmacy, Akkalkuwa, District Nandurbar, MS, India

Published In:   Volume - 4,      Issue - 5,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4514  

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ABSTRACT:
A significant portion of active compounds in herbal medicines shows strong bioactivity in vitro, but much lower effectiveness in vivo due to their poor lipid solubility and unsuitable molecular size. These factors lead to limited absorption and low bioavailability of the active ingredients from herbal extracts. Herbosome technology helps overcome this challenge by improving the bioavailability of herbal extracts. Acting as a link between conventional and advanced drug delivery systems, herbosomes are complexes formed by natural active ingredients and phospholipids (such as phosphatidylcholine and phosphatidylserine), which enhance the absorption of herbal compounds. This innovative technique is emerging as a valuable approach in phytopharmaceuticals to boost the medicinal potential of herbal extracts. The article provides an overview of herbosome technology, its recent developments, applications for standardized herbal extracts, and offers comprehensive scientific insights and characterization of herbosomes as a promising drug delivery system.

Cite this article:
Shaikh Samrin Mohammad Tufail*, Kashtriya Jayshri Prakash, Kazi Shifa Abdul Wadood. Formulation and Characterization of Herbosome: A Review . IJRPAS, May 2025; 4 (5): 167-173.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4514


1.      Santos AC, Veiga F, Ribeiro AJ. Applications of novel drug delivery System for herbal formulations. Fitoterapia. 2010; 81:680.

2.      Manach C, Scalbert A, Morand C, Remesy C, Jimenez L. Polyphenols: Food sources and bioavailability. Am J Clin Nutr. 2004; 79:727-47.

3.      Bombardelli E, Curri SB, Della Loggia R, Del Negro P, Tubaro A et al. Complex between phospholipids and vegetal derivatives of biological Interest. Fitoterapia 1989; 60:1-9.

4.      Mauri PL, Simonetti P, Gardana C, Minoggio M, Morazzoni P, Bombardelli E et al. Liquid chromatography atmospheric pressure Chemical ionization mass spectrometry of terpene lactones in plasma of Volunteers dosed with Ginkgo biloba L. extracts. Rapid Commun Mass Spectrom. 2001; 15:929 34.

5.      Tawheed A, Bhat SV. A review on phytosome technology as a novel Approach to improve the bioavailability of nutraceuticals. Int J Adv Res Techno. 2012; 43-57.

6.      Sharma S, Tripathi P. Role of traditional herbal medicine in eczema: A Review. Pharmacogn Rev. 2014; 8(16):94-101. Doi:10.4103/0973-7847134229

7.      Alam M, Tripathi J, Khan M, et al. Pharmacological activities of Berberis Aristata – A review. J Appl Pharm Sci. 2012; 2(6):24-31.

8.      Srivastava JK, Shankar E, Gupta S. Chamomile: A herbal medicine of the Past with a bright future (Review). Mol Med Rep. 2010; 3(6):895-901.Doi:10.3892/mmr.2010.377

 

9.      U Citernesi, M Sciacchitano. Phospholipids active ingredient Complexes. Cosm Toil 1995;110:57-68.

10.  Ravi GS, Chandur V, Shabaraya ARK. Phytosomes: an advanced Herbal drug delivery system. IJPRBS 2015;4:415-32.

11.  Bombardelli E, Mustich G. Bilobalide phospholipid complex, Their uses and formulation containing them, U. S. Patent; 1991.

12.  Valenzuela A, Aspillaga M, Guerra R. Selectivity of silamarin on The increase of glutathione containing in different tissues of Rat. Plant Med 1989;55:42.

13.  Maiti K, Kakali M, Arunava G, Bishnu PS, Pulok KM. Curcumine Phospholipid complex: Preparation,therapeutic evaluation and Pharmacokinetic study in rats. Int J Pharm 2007;330:155-63.

14.  Singh RP, Parpani S, Narke R, Chavan R. Phytosome: recent Advance research for novel drug delivery system. Asian J Pharm Res Dev 2014;2:15-29.

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