International Journal of Research in Pharmacy and Allied Science

ISSN: 2583-6544   |  Issues per year: Monthly  |   Indexed In: Google Scholar, CORE, ScienceOpen, Researchgate

ISSN:2583-6544

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Microwave-Assisted Organic Synthesis: A Green Chemistry Strategy

Author(s): Mugdivari Sangeetha*1, Balemla Sada2, Kunal Bohara3, Syed Yaseen Pasha4, Yerram Shravya5, Tadikonda Rama Rao6

Email(s): 1sangeetha.kodiganti@gmail.com

Address:

    CMR College of Pharmacy, Kandlakoya, Medchal, Hyderabad, Telangana,India-501401

Published In:   Volume - 4,      Issue - 6,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4605  

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ABSTRACT:
Microwave-Assisted Organic Synthesis (MAOS) has emerged as a revolutionary approach in green chemistry, offering an energy-efficient, environmentally friendly alternative to traditional synthetic methods. Conventional organic synthesis faces challenges such as excessive reaction times, high solvent consumption, and significant chemical waste. Microwave irradiation enhances reaction efficiency by selectively heating the reaction mixture, leading to faster reaction rates, improved yields, and reduced byproduct formation. This technique aligns with the principles of green chemistry by minimizing toxic solvent use and optimizing reaction conditions for sustainability. The fundamental mechanisms of microwave heating, including dipolar polarization and ionic conduction, enable precise and uniform energy transfer, making it an effective tool for various organic transformations. Comparative studies on the synthesis of compounds like phenacetin, benzoic acid, and sulfonyl chloride demonstrate the advantages of MAOS over conventional methods. Despite certain limitations, such as safety concerns and solvent-specific absorption issues, MAOS is poised to become a mainstream technique in synthetic chemistry, driving advancements in eco-friendly and efficient chemical processes.

Keywords:

Cite this article:
Mugdivari Sangeetha, Balemla Sada, Kunal Bohara, Syed Yaseen Pasha, Yerram Shravya,Tadikonda Rama Rao. Microwave-Assisted Organic Synthesis: A Green Chemistry Strategy. IJRPAS, June 2025; 4 (6): 50-62.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4605


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