International Journal of Research in Pharmacy and Allied Science

ISSN: 2583-6544   |  Issues per year: Monthly  |   Indexed In: Google Scholar, CORE, ScienceOpen, Researchgate

ISSN:2583-6544

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Enhanced Topical Therapeutics: A Review on Development and Evaluation of Innovative Emulgel Formulations

Author(s): Pathan Junaid Moinuddin2*1, Mujahid Ahmed Haroon Rasheed22, Mr. Faizan Ahmed13, Obaidurraheman Mohammed Saleem24

Email(s): 1mujahidpharm22@gmail.com

Address:

    1. Assistant Professor, Dept. of Pharmaceutical Chemistry, Royal College of Pharmaceutical Education and Research, Syne Khurd Malegaon. 2. B Pharmacy Royal College of Pharmaceutical Education and Research, Syne Khurd Malegaon

Published In:   Volume - 4,      Issue - 10,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.41012  

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ABSTRACT:
Topical drug delivery is a preferred approach for treating skin disorders due to its ability to provide localized therapy with minimal systemic exposure. Conventional dosage forms such as ointments, creams, and gels often face challenges like poor spreadability, limited penetration, and low patient compliance. Emulgels, combining the advantages of emulsions and gels, have emerged as an innovative solution to these limitations. These formulations, available as oil-in-water or water-in-oil systems, incorporate gelling agents, emulsifiers, and penetration enhancers to optimize drug delivery through the skin. This review highlights the rationale for emulgel development, ideal drug properties, key excipients, preparation methods, and evaluation parameters including rheology, spreadability, pH, skin irritation, and in-vitro drug release. Emulgels offer improved solubility, controlled release, better patient compliance, and enhanced permeation of both hydrophilic and hydrophobic drugs. Despite minor limitations, emulgels represent a versatile and promising platform for advanced topical therapeutics in dermatology and cosmeceuticals.

Keywords:

Cite this article:
Pathan Junaid Moinuddin, Mujahid Ahmed Haroon Rasheed,Mr. Faizan Ahmed, Obaidurraheman Mohammed Saleem. Enhanced Topical Therapeutics: A Review on Development and Evaluation of Innovative Emulgel Formulations. IJRPAS, October 2025; 4(10): 156-168.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.41012


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