International Journal of Research in Pharmacy and Allied Science

ISSN: 2583-6544   |  Issues per year: Monthly  |   Indexed In: Google Scholar, CORE, ScienceOpen, Researchgate

ISSN:2583-6544

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New-insight Management Implications of Diabetic Autonomic Neuropathy: Future Perspectives

Author(s): Nikita Singh1, Ankita Kumari2, Ladli Kishore*3

Email(s): 1llekn41bit@gmail.com

Address:

    Maharaja Agrasen School of Pharmacy, Maharaja Agrasen University, Solan, H.P., India

Published In:   Volume - 4,      Issue - 1,     Year - 2025

DOI: https://doi.org/10.71431/IJRPAS.2025.4106  

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ABSTRACT:
Diabetic Neuropathic (DN) disorders are emerges in the peripheral nerve system's somatic and autonomic parts. A number of organs are connected by motor, sensory, and vasomotor fibers that are impacted by Diabetic Autonomic Neuropathy (DAN). As a result, DAN may impact several organ systems, including the Gastrointestinal, Cardiovascular, and Genitourinary. The pathophysiology of DN encompasses protein kinase C activation, polyol pathway flux, oxidative stress, and advanced end products of glycation, all of which lead to microvascular conditions and nerve damage. Poorly understood and underappreciated, treatment-induced neuropathy due to diabetes is an iatrogenic consequence of stringent glucose control in diabetics. Diabetic neuropathy has now few effective treatments options. Researching safe and effective medications to treat metabolic disorders is crucial since phytopharmaceuticals are well-known as having important roles in medicine. Finally, this review article can encourage physicians and researchers to do well-studied research to find a new therapy and management to improve metabolic control with DAN disorder; hence this study may be proven to be effective for DAN patients.

Keywords:

Cite this article:
Nikita Singh, Ankita Kumari, Ladli Kishore. New-insight Management Implications of Diabetic Autonomic Neuropathy: Future Perspectives. IJRPAS, Nov-Dec 2024; 3(6): 63-71.DOI: https://doi.org/https://doi.org/10.71431/IJRPAS.2025.4106


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