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Author(s): Momin Zain1, Shaikh Arbaz2, Shaikh Adnan3, Rehan Deshmukh4

Email(s): 1mominzain527@gmail.com

Address:

    JIIU’s Ali-Allana Collage of Pharmacy, Akkalkuwa Dist: Nandurbar, Maharashtra-425415

Published In:   Volume - 3,      Issue - 5,     Year - 2024

DOI: Not Available

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ABSTRACT:
Natural polymers, derived from renewable resources, have gained significant attention as pharmaceutical excipients in solid oral dosage forms due to their biocompatibility, biodegradability, and sustainability. This review article provides a comprehensive overview of the applications, properties, and advances of natural polymers as excipients in solid oral dosage forms, including tablets, capsules, and powders. We discuss the roles of natural polymers such as starch, cellulose, gelatin, chitosan, and pectin in controlling drug release, improving tablet strength and disintegration, enhancing lubrication and coating, and enabling mucoadhesion and taste masking. The review highlights the latest developments in natural polymer chemistry and technology, including modifications and derivatives, nanotechnology, and composite materials. We also examine the regulatory considerations, challenges, and future directions for the use of natural polymeric excipients in solid oral dosage forms. By summarizing the current state of knowledge and highlighting emerging trends, this review aims to inspire innovation and optimization in the design and development of solid oral dosage forms using natural polymeric excipients.

Cite this article:
Momin Zain, Shaikh Arbaz,Shaikh Adnan, Rehan Deshmukh.Applications of Natural Polymers as Pharmaceutical Excipients in Solid Oral Dosage Forms. IJRPAS, Sept – Oct 2024; 3(5): 26-33.


1.   Goswami S, Naik S. Natural gums and its pharmaceutical application. JSci Inn Res 2014;3:112-121.

2.      Dharmendra S, Surendra JK, Sujata M, Shweta S. Natural excipients: A review. Int J Pharm Bio Arch 2012;3:1028-1034.

3.      Lam K.S., New aspects of natural products in drug discovery, Trends Microbiol. 2007; 15 : 279-89.

4.      Vicky V. Mody, Introduction to Polymeric Drug Delivery, Internet Journal of Medical Update, 5(2): 2010 July;1‐2.

5.      Taylor and Francis, Polymers in Drug Delivery System, 2006, 1‐236.

6.      Park, K. and Robinson, J.R., Bioadhesive polymers as platforms for oral‐controlled drug delivery: method to study bioadhesion, Int. J. Pharm., 19, 1984, 107.

7.      Chang, H.S., Bioadhesive polymers as platforms for oral controlled drug delivery II: synthesis and evaluation of some swelling, water‐insoluble bioadhesive polymers, J. Pharm. Sci., 74(4), 1985, 399.  

8.      Varshosaz, J.; Tavakoli, N.; Eram, S.A.  Use of natural gums and cellulose derivatives in production of sustained release Metoprolol tablets.  Drug Deliv. 13,2006, 113‐119.

9.      Antony PJ, Sanghavi NM. A new disintegrant for pharmaceutical dosage forms. Drug DevInd Pharm 1997;23:413-415.

10.  Owen SC. In Raymond CR, Paul JS, Paul JW (eds.), Handbook of Pharmaceutical Excipients. The Pharmaceutical Press and the America Pharmaceutical Association 2003;654-656.

11.  Kibbe AH. In C. R. Raymond, J. S. Paul, J. W. Paul (eds.), Handbook of Pharmaceutical Excipients. The Pharmaceutical Press and the American Pharmaceutical Association 2003;271-273.

12.  Heda A, Shivhare U. Study of some natural hydrophilic polymers as matrix forming materials for sustained release tablet formulation. Int J Pharm Exp 2004;69-74.

13.  Shefter E. In C. R. Raymond, J. S. Paul, J. W. Paul (eds.), Handbook of Pharmaceutical Excipients. The Pharmaceutical Press and the American Pharmaceutical Association 2003;1- 2.

14.  Clochard M, Dinand E, Rankin S, Simic S, Brocchini S, New strategies for polymer development in pharmaceutical science‐a short review, J Pharm Pharmacol, 2001, 53(9),1175‐ 1184.

15.  OmanathanuPillai, Ramesh, Polymers in drug delivery, Current Opinion in chemical biology, Vol 5, issue 4, 2001, 447‐451.

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