ABSTRACT:
Nigella sativa (N. sativa) (Family Ranunculaceae) has been used as a curative remedy for thousands of years. N. sativa seed exhibits a wide range of pharmacological activities, including immunopotentiation, antihistaminic, anti-hypertensive, anti-inflammatory, and antimicrobial properties. It contains thymoquinone, thymohydroquinone, dithymoquinone, p-cymene, carvacrol, 4-terpineol, t-anethol, sesquiterpene longifolene, nigellicimine and nigellicimine-N-oxide, -pinene, and thymol, among other things. The incalculable medicinal properties and therapeutic applications of N. sativa demonstrate its value as a valuable medicinal plant. The goal of this review is to summarize some important pharmacological studies and phytochemical investigations on N. sativa and isolated principles that can be further investigated in the search for novel molecules in the search for novel herbal drugs.
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