Abstract View

Author(s): Ms. Vaishnavi D. Patil1, Ms. Sayali D. Patil2, Mr. Azam Z. Shaikh3, Dr. S. P. Pawar4

Email(s): 1azamph46@gmail.com

Address:

    Department of Pharmaceutics P.S.G.V.P.M’s College of Pharmacy, Shahada

Published In:   Volume - 2,      Issue - 2,     Year - 2023

DOI: Not Available

 View HTML        View PDF

Please allow Pop-Up for this website to view PDF file.

ABSTRACT:
Antibiotics are powerful medicines that treat certain infections and, when used correctly, can save lives. They either prevent the growth of bacteria or destroy them. Normally, the immune system can kill bacteria before they can multiply and cause symptoms. White blood cells (WBC) attack harmful bacteria. Even when symptoms appear, the immune system is usually able to manage and fight off the infection. However, there are times when the number of harmful bacteria is too large for the immune system to eliminate them all. Antibiotics can help in this scenario. The first antibiotic was penicillin. Penicillin-based antibiotics such as ampicillin, amoxicillin, and penicillin G are still available and have been used for many years to treat a variety of infections. There are several types of modern antibiotics that are usually available only by prescription in the United States. Topical antibiotics are available in over-the-counter (OTC) creams and ointments. Modern medicine has changed as a result of antibiotics. They facilitate critical therapies and procedures and are crucial for the treatment of infectious disorders. Nevertheless, despite their popularity, their continued usage in the twenty-first century is threatened by two unrelated problems. The first is that over time, the bacteria that these medications are meant to kill develop a tolerance to them. The second is that traditional mechanisms of payment are no longer cost-effective for discovering and developing antibiotics. As a result, there are fewer businesses and research facilities focused on producing new antibiotics, creating a pipeline that is anemic and endangers our ability to control diseases.

Cite this article:
Ms. Vaishnavi D. Patil, Ms. Sayali D. Patil, Mr. Azam Z. Shaikh, Dr. S. P. Pawar. A Review on Antibiotics as Drug and Poison. IJRPAS, 2023; 2(2): 1-9.



1.        Antibiotics. NHS. 5 June 2014.

2.        Why antibiotics can't be used to treat your cold or flu 6 May 2017.

3.        "General Background: Antibiotic Agents". Alliance for the Prudent Use of Antibiotics. Archived from the original on 14 December 2014.

4.        The past, present, and future of antibiotics. Michel A. Cook Gerard D. Wright

5.         Laxminarayan R, Duse A, Wattal C, Zaidi AK, Wertheim HF, Sumpradit N, et al. (December 2013). "Antibiotic resistance-the need for global solutions". The Lancet. Infectious Diseases

6.        Considerations for determining if a natural product is an effective wound-healing agent. The International Journal of Lower Extremity Wounds Lindblad WJ (June 2008)..

7.        Forrest RD (March 1982). "Early history of wound treatment". Journal of the Royal Society of Medicine.

8.        Calderon CB, Sabundayo BP (2007). Antimicrobial Classifications: Drugs for Bugs. In Schwalbe R, Steele-Moore L, Goodwin AC. Antimicrobial Susceptibility Testing Protocols. CRC Press. Taylor & Frances group

9.        Calderon CB, Sabundayo BP (2007). Antimicrobial Classifications: Drugs for Bugs. In Schwalbe R, Steele-Moore L, Goodwin AC. Antimicrobial Susceptibility Testing Protocols. CRC Press. Taylor & Frances group

10.    Frith J. "Arsenic – the "Poison of Kings" and the "Saviour of Syphilis"". Journal of Military and Veterans' Health.

11.    Aminov RI (2010). "A brief history of the antibiotic era: lessons learned and challenges for the future". Frontiers in Microbiology.

12.    Irish contributions to the origins of antibiotics. Irish Journal of Medical Science.Kingston W (June 2008).

13.    Alexander Fleming (1881-1955): Discoverer of penicillin. Singapore Medical Journal.an SY, Tatsumura Y (July 2015).

15.    Sykes R (2001). "Penicillin: from discovery to product". Bulletin of the World Health Organization.

16.     Van Epps HL (February 2006). "René Dubos: unearthing antibiotics". The Journal of Experimental Medicine.

17.    Capocci M (1 January 2014). "Cold drugs. Circulation, production and intelligence of antibiotics in post-WWII years". Medicina Nei Secoli

18.    Kahn LH. Antimicrobial resistance: A one health perspective. Trans R Soc Trop Med Hyg. 2017;111:255–60.

20.    Penicillins Drugs.com Medically reviewed by C. Fookes, BPharm. Last updated on April 5, 2018.

21.    Cephalosporins Drugs.com Medically reviewed by C. Fookes, BPharm on July 20, 2018.

22.    Macrolides Healthgrades.Medically Reviewed By William C. Lloyd III, MD, FACS — Written By Sarah Lewis, PharmD Updated on April 27, 2021

23.    Quinolones drugs.com Written by C. Fookes, BPharm on April 12, 2018.

24.    Sulfonamide drugs: structure, antibacterial property, toxicity, and biophysical interactions Aben Ovung, Jhimli Bhattacharyya. 2021 Mar 29.

25.     Tetracycline NIH Mollie C. Shutter; Hossein Akhondi. Last Update: July 4, 2022.

26.    Side effects, Antibiotics. NHS. 5 June 2014.

27.    National Estimates of Emergency Department Visits for Antibiotic Adverse Events Among Adults—United States, 2011–2015Andrew I. GellerMaribeth C. LovegroveNadine Shehab, PharmD, Lauri A. HicksMathew R. P. Sapiano, and Daniel S. Budnitz.

28.    Clostridium difficile infection: a review of current and emerging therapies Andrew Ofosu 2016 Apr-Jun

29.    Bhullar K, Waglechner N, Pawlowski A, et al. Antibiotic resistance is prevalent in an isolated cave microbiome.

Related Images:



Recent Images



RPHPLC Method for Concurrent Determination of Haloperidol and Trihexyphenidyl in API and Combined Tablet Formulations
A review on HPLC Methods for Estimation of Travoprost  in Combined and Single Pharmaceutical formulation and Bulk
To Study number and types of refund Medicines from different Wards of Hospital to the In-Patient Pharmacies
A Novel RP-HPLC Analytical Method Development and Validation of Berberine In Bulk and Polyherbal Formulation
Formulation and Evaluation of A Polyherbal Cough Syrup with Potential Anti-Obesity Effects
Formulation and evaluation of Herbal Face Cream
Formulation and In-vitro Evaluation of Cold Cream
Prevalence study of Diabetes Mellitus
Design and Optimization of Extended-Release Mini-Tablets of Metoprolol Succinate Using Okra Stalk Powder and HPMC K100 M as Release Modifiers
Comprehensive review on Alfuzosin quantification: Analytical techniques and the evolution of AQbD in method development

Tags


Recomonded Articles:

Author(s): Bhagyashri C. Patel; Sandhya R. Chavhan; H.P. Suryawanshi; R. A. Ahirrao

DOI:         Access: Open Access Read More

Author(s): Pravin V. Gomase; R. R. Patil; Sunil P. Pawar

DOI: NA         Access: Open Access Read More

Author(s): Kamil Hafiz Anees Ahmed Quazi; Dr. Majaz Quazi; Wasil Jalees Quazi; Dr. G. J. Khan.

DOI:         Access: Open Access Read More

Author(s): Shaikh Aminoddin Raisoddin; Shifa Maniya; Sayeeda Begum; Naziya Shaikh.

DOI:         Access: Open Access Read More

Author(s): Harshadeep Seal; Namrata Koushik

DOI:         Access: Open Access Read More

Author(s): Magendran Rajendiran1*, Muruganand R2, Abhisek Kumar Sinha2, Mohamed Raashith M S2, Jasitha Begam M2, Usharani G2, Dhivyari D2, Deepika T2

DOI: https://doi.org/10.71431/IJRPAS.2025.4413         Access: Open Access Read More

Author(s): Soni Rishita1*, Salunke Khushi1, Patel Harsh1, Patel Aastha1, Taufik Mulla2, Ambika Nand Jha3

DOI:         Access: Open Access Read More

Author(s): Mehul P. Bagde; Mukesh Rajpurohit; Lalit Chaudhary

DOI:         Access: Closed Access Read More

Author(s): Lilachand B. Patil; Khushal K. Chaudhari; Eknath Jagannath Patil

DOI:         Access: Open Access Read More

Author(s): Mohammad Zaid*; Prof. Imran Kalam; Dr. Quazi Majaz

DOI:         Access: Open Access Read More

Author(s): Kishor S. Rathi*; Diksha S. Bramhane; Chetana A. Karankal , Dr. Ravindra R. Patil

DOI:         Access: Open Access Read More

Author(s): Mahesh Dilip Mane; Nilesh Shashikant Patole; Vetal Nana Kodalkar; Sanket Arun Metkari.

DOI:         Access: Open Access Read More

Author(s): Mohammad Vakar*; Shaikh Imran Kalam; Dr. G.J. Khan; M Sohil M Shabbir; Aman Shaikh; Shaikh Md. Moiz

DOI:         Access: Open Access Read More

Author(s): Venkatesh; Chaithra N; Parthasarathi K Kulkarni; Siddartha H N; Hanumanthachar Joshi K

DOI:         Access: Open Access Read More

Author(s): Apurva Arabhavi; Manisha Mane; Neha Desap Sachin Mali; Akanksha Sawant.

DOI:         Access: Open Access Read More

Author(s): Jayesh M. Rajput

DOI:         Access: Open Access Read More

Author(s): Vaibhav S. Jadhav; Vishwajeet G. Thorat; Priyanka V. Gawali; Dr. Balmukund R. Rathi

DOI:         Access: Open Access Read More

Author(s): Mansoori Safwan Salim; Prof. Rehan Deshmuhk; Dr. G.J. Khan; Shaikh Amaan; Sayyed Ahamad Sayyed Kaleem; Hamza Iliyas Amliwala

DOI:         Access: Open Access Read More

Author(s): Mansuri Jahid; Rehan Deshmukh; Khan Ramiz.V; Sayyed Anas Ali

DOI:         Access: Open Access Read More