ABSTRACT:
The development for the targeted delivery when it was investigated a drug delivery mechanism that would target directly to the diseased cell. In noisome, the vesicles forming amphiphile is a non-ionic surfactant which is usually stabilized by addition of cholesterol and small amount of anionic surfactant. Nonionic surfactant vesicles have been seen lot of advantage in the area of novel drug delivery systems due to their salient features such as biodegradable, biocompatible, chemical stable, less production cost, easy to store, easy to handle and low toxicity. The niosomes are classified as a function of the number of bilayers or as a function of size or as a function of the method of preparation. We discuss the method of preparation and also the evaluation parameters of the niosomal preparation. The application of niosomes technology is widely varied and it can be used to treat a number of diseases.