A Prospective Observational Study on the Clinical Evaluation of Vertigoin
Young Adult Population of Amaravati Capital Region
Sreenu Thalla,* Bhukya Moshe Nayak. Jakkampudi Nikhitha, Datla Bhavya
Reddy, Nemalikanti Viharika, Puttagunta Srinivasa Babu
Vignan Pharmacy College (Autonomous),
Vadlamudi, Guntur, Andhra Pradesh - 522213
*Correspondence: sreenuthalla87@gmail.com
DOI: https://doi.org/10.71431/IJRPAS.2026.5713
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Article
Information
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Abstract
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Review Article
Received: 23/07/2026
Accepted: 26/07/2026
Published:31/07/2026
Keywords
Vertigo; BPPV; Amaravati;
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Background: Vertigo, which is exacerbated by head movement, is
the feeling of movement or spinning when none is happening. It is frequently
accompanied by nausea, perspiration, or trouble walking. It is the most prevalent type of vertigo
and is frequently brought on by vestibular neuritis, Ménière's disease and
benign paroxysmal positional vertigo (BPPV).
Stroke, brain tumors, multiple sclerosis, migraines, trauma and
exposure to toxins are fewer common causes.
Unlike other forms of dizziness, such as presyncope or disequilibrium,
vertigo typically indicates an issue with the vestibular system. A prospective observational research design
was used for the investigation.
Result: Vertigo in 1,670 young people was investigated in this
6-month research conducted in Amaravati.
Positional alterations were responsible for 45.8% of instances of
dizziness and unsteadiness, which were prevalent (65.2%). The most common causes were BPPV (37.9%)
and vestibular migraine (25.6%). Among
the treatments were medicine (56.3%), lifestyle modifications (21.2%), and
physical therapy (22.5%). With 83.1%
of patients reporting alleviation, physical therapy was quite successful in
treating BPPV. The study emphasizes
how common vertigo is in young adults and the need for focused treatments as
well as more investigation into long-term effects.
Conclusion: The high frequency of vertigo among young
individuals in the Amaravati Capital Region emphasizes the importance of
early diagnosis and complete treatment. This study highlights significant
risk variables, including lifestyle and environmental factors, and lays the
groundwork for future research into focused prevention, timely intervention,
and effective treatment techniques..
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INTRODUCTION:
Vertigo
is the sensation of spinning or movement when none exists, often accompanied by
nausea, vomiting, balance problems, typically worsened by head movements. It is
classified into two types: peripheral
vertigo, caused by inner ear disorders such as benign paroxysmal positional
vertigo (BPPV), Ménière’s disease, vestibular neuritis; and central vertigo.
Peripheral vertigo is more common and frequently caused by disruptions in the
vestibular system. BPPV, the most common cause of positional vertigo, results
from displaced calcium crystals (otoconia) in the semicircular canals—most
often the posterior canal—leading to brief spinning episodes during head
movements [1]. Ménière’s disease causes recurrent vertigo, tinnitus,
hearing loss, and ear fullness, affecting approximately 17–200 people per
100,000 worldwide; its causes may include viral infections, detached otoconia,
or anatomical change[2] Vestibular neuritis is typically linked to viral
infections or ischemia, causing inflammation and vestibular dysfunction [3].Central vertigo arises from lesions in the brainstem or
cerebellum due to stroke, tumors, multiple sclerosis, or head injuries, with
30–65% of patients experiencing vertigo or imbalance [4]. Vestibular migraines, transient ischemic attacks, and
vascular conditions such as hypertension, atherosclerosis, embolism, and
aneurysms can also cause central vertigo[5][6].Other causes include vestibular schwannomas, benign
tumors of the vestibular nerve that cause unilateral vertigo, hearing loss, and
tinnitus [7]. Superior semicircular canal dehiscence syndrome
(SSCDS) caused by a bony defect producing abnormal responses to loud sounds or
pressure. Chronic dizziness—a persistent, non-rotational sense of unsteadiness
often worsened in visually complex environments[8].Accurate diagnosis, often using the HINTS exam, is
essential to differentiate between peripheral and central vertigo [9].Dizziness, which includes symptoms like
light-headedness, unsteadiness, and presyncope, lacks a precise definition and
may stem from peripheral or central vestibular causes [10]. Diagnostic accuracy improves by focusing on symptom
timing, triggers, and using the HINTS exam, which can outperform early
neuroimaging in AVS cases [11]. BPPV is the most common cause, especially in older
adults, with posterior canal BPPV accounting for over 80% of cases [12]. Other causes include vestibular neuritis,
labyrinthitis (viral or bacterial) vestibular migraine and Meniere’s disease,
which causes vertigo, tinnitus, and fluctuating hearing loss. Peri lymphatic
fistula may result from trauma or surgery and presents with dizziness triggered
by pressure or sound (Hennebert's, Tullio's signs) [13]. Patients with vertigo/dizziness have a significantly
higher risk of stroke or cardiovascular events[14].BPPV prevalence rises with age, being seven times
higher in those over 60 [15]. Vertigo can be triggered by head movements and
postures, with shifting positions being the most common cause, affecting about
half of individuals during standing or walking [16]. Complications of otitis media can lead to facial
paralysis, labyrinthitis, and chronic ear infections [17]. Labyrinthitis can result from infections spreading
from the middle ear, causing severe vertigo, nausea, and hearing loss, and in
chronic cases, leading to labyrinthine ossification [18]. Comorbidities such as diabetes, hypertension,
osteoporosis, and depression are commonly seen in older adults with BPPV [19]. These findings highlight the complex relationship
between vertigo, comorbidities, and its increased prevalence with age.The
rotatory chair test, a less commonly used vestibular function test, is valuable
for measuring the vestibulo-ocular reflex (VOR), particularly in cases of
bilateral vestibular hypofunction. It simulates the natural push-pull
characteristics of the horizontal semicircular canals (SCCs) and generates
nystagmus in most individuals, with only those with profound bilateral
vestibular hypofunction showing no nystagmus. Dynamic visual acuity (DVA) tests
evaluate VOR by assessing gaze stability during head motion [20]. The Head Impulse Test (HIT) can be used at the bedside
to assess VOR, although it has limitations in sensitivity and specificity
Pathological HIT is typically associated with peripheral vestibular lesions but
may also occur in certain central lesions, such as strokes [21]. Ocular Tilt Reaction (OTR) and Subjective Visual
Vertical (SVV) tests are used to differentiate between central and peripheral
vestibular dysfunction, with pronounced skew deviation (SD) [22].Romberg, Jendrassik, and balance tests like Single Leg
Stance, Tandem Gait, and the Timed Up and Go test further assess stability,
with positive tests indicating vestibular dysfunction. For instance, in Romberg
testing, the Jendrassik maneuver increases test difficulty, and a test is
positive if the subject moves before 30 seconds. In the Single Leg Stance test,
the subject must maintain balance with eyes open or closed for up to 30 seconds.
The Tandem Gait test requires walking heel-to-toe for 20 steps, and the Timed
Up and Go test measures the time it takes to rise, walk 3 meters, turn, and
return to the chair. These tests are vital for diagnosing vestibular issues and
evaluating the severity of dysfunction [23].
Vertigo treatment primarily involves
vestibular suppressants and antiemetics. Anticholinergics like scopolamine
reduce nystagmus [24]. Antihistamines help prevent motion sickness and
vertigo symptoms but have side effects [25]. Benzodiazepines, such as lorazepam, are effective at
low doses but can cause habituation and memory issues[26]. Calcium channel antagonists, like cinnarizine, are
used in Meniere’s disease but are not universally accepted [27]. Antiemetics, such as meclizine, treat nausea, while
dopamine antagonists like prochlorperazine are second-line due to side effects[28].For BPPV, physical therapy is the primary treatment,
with meclizine helping with nausea [29].In Meniere’s disease, vestibular suppressants manage
acute attacks, while salt restriction and diuretics may reduce attacks [30]. Vestibular neuritis is managed with minimal medication
and activity encouragement to aid recovery [31]. Bilateral vestibular paresis is typically caused by
ototoxic antibiotics like gentamicin following infections such as osteomyelitis
or peritonitis. [32]. Central vertigo, a rarer cause (5% of cases in ER
settings), is mainly due to vascular disorders like stroke or migraine, with
prolonged symptoms. Common treatments include verapamil, amitriptyline, and
benzodiazepines. For migraine-related vertigo, SSRIs and β-blockers can also be
used. In patients with known CNS lesions, benzodiazepines like lorazepam and
prochlorperazine may help. Gabapentin, carbamazepine, or acetazolamide may be
used for specific vertigo conditions [33]. Psychogenic vertigo, linked to psychiatric disorders
such as anxiety or depression, is treated with psychiatric interventions.
Benzodiazepines are effective for anxiety, while SSRIs may help with
depression. In cases of somatization or malingering, no medication is
prescribed, but reducing unnecessary healthcare usage is the goal [34]. When the cause of vertigo is undetermined, the
treatment is empirical, often involving a medication withdrawal strategy and
trials of meclizine, clonazepam, or migraine treatments like verapamil.
Monitoring is essential, as conditions like Meniere’s disease or acoustic
neuromas may evolve over time [35].
METHODOLOGY
STUDY DESIGN: It is a prospective observational study
STUDY PERIOD: The study was conducted for 6 months (July 2024 to December 2024).
STUDY METHOD: This study was conducted in
Vignan Pharmacy College, Vadlamudi, Guntur. This study involves
all the subjects who were included
in the inclusion and exclusion
criteria. Subjects are observed for their provoking
factors, incidence and prevalence of emergency cases. An informed
consent form will be taken from the participant.
SAMPLE SIZE: 518 (offline) and 1152 (online)
young adults.
STUDY
MATERIALS: Patient data collection form,
Patient consent form
STATISTICAL ANALYSIS: The obtained
data was statistically analysed and the results were represented by using SPSS Software Version 23.0.
INCLUSION CRITERIA: Patients aged 18 years and above, Patients who provide informed
consent to participate in the study.
EXCLUSION CRITERIA: Patients with incomplete medical records,
Inability to provide informed
consent, psychologically disabled
patient.
RESULTS & DISCUSSIONS
For Online Data
Table 1: Age Vs No. of Participants
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Age
|
No.
of Participants
|
Percentage
(%)
|
Mean
+/- SD
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18
|
370
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32.11%
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22.3
± 3.35 years
|
|
19
|
224
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19.44%
|
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20
|
190
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16.49%
|
|
21
|
153
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13.28%
|
|
22
|
90
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7.81%
|
|
23
|
68
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5.90%
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24
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24
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2.08%
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25
|
33
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2.86%
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Depicts the information regarding
the distribution of study subjects within the age groups of 18 years to 25
years. Majority of the subjects were found within the age of 18 years (32.11%),
followed by 19 years (19.44%), 20 years (16.49%), 21 years (13.28%), 22 years
(7.81%), 23 years (5.90%), 24 years (2.08%) and 25 years (2.86%).
Table 2: Gender Vs No.
of Participants
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Gender
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No.
of participants
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Percentage
(%)
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Mean+/-SD
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Male
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627
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54.16%
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1.46 ± 0.50
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Female
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525
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45.57%
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Comprising 525 women (45.57%) and 627 men (54.17%), the study
had an average age of 1.46 ± 0.50 years. With an average vertigo annoyance
score of 2.42, which indicates considerable discomfort, Hackenberg et al.'s study
of 8,519 individuals, on the other hand, revealed a vertigo prevalence of
21.6%, peaking in the 55–64 age range. These findings imply that the occurrence
and effects of vertigo differ considerably by demographic and age [36].
Table 3: Level of Education Vs No. of
Participants
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Level of Education
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No. of participants
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Percentage
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Mean +/- SD
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High School
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59
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5.121%
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2.23 ± 0.59
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Undergraduate
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811
|
70.39%
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Graduate
|
242
|
21.00%
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Other
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40
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3.47%
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Depicts the information regarding
the level of education of the participants from high school to graduates and
others. Majority of the participants were found as under graduates (70.39%),
followed by high school (5.121%), graduates (21.006%) and others (3.472%).
Table 4: Individual no. of responses for
question 1
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Do
you have any known medical condition
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No. of participants
|
Percentage (%)
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Mean
+/- SD
|
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Yes
|
361
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31.33%
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1.69
± 0.46
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No
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792
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68.75%
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In our survey of 1,153 people, 31.33% reported having a
recognized medical condition, whereas 68.75% did not. Similarly, Sreenivas V et al. discovered that 45.1% of patients had hypertension, with
hypertensive patients having greater recurrence rates (38.1%) than
non-hypertensive patients (16%), implying a possible relationship between
hypertension and recurrence [37].
Table 5: Individual no. of responses for
question 2
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Have you had any of
the following in the past?
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No. of participants
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Percentage (%)
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Mean +/- SD
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Migraines
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160
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13.88%
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4.35 ± 1.62
|
|
Ear infection
|
99
|
8.59%
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Neurological disorder
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31
|
2.69%
|
|
Head trauma
|
73
|
6.33%
|
|
others
|
664
|
57.63%
|
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Multiple conditions
|
125
|
10.85%
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Participants in our study reported migraines (13.88%), ear
infections (8.59%), neurological illnesses (2.69%), head injuries (6.33%),
others (57.68%), and multiple conditions (10.85%). These findings are
consistent with Marcello Cherchi et al., who connected vestibular
migraine (VM) to otologic diseases, and Faith W. Akin et al., who discovered
that many patients with Meniere's disease also fit migraine criteria. The
presence of numerous illnesses emphasizes the intricate link between VM and other
medical concerns [38].
Table 6: Individual no. of responses for
question 3
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Are you currently
taking any medications?
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No of Participants
|
Percentage (%)
|
Mean +/- Standard
Deviation
|
|
Yes
|
240
|
20.83%
|
1.79 ± 0.41
|
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No
|
912
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79.16%
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In our survey, 20.83% of individuals said they took drugs,
whereas 79.16% didn't. In contrast, Benedict Katzenberger et al.
discovered that 35% of 158 patients with vertigo and balance difficulties were
taking anticholinergic or sedative drugs, which were connected to impaired
functioning. The reduced medication use in our younger sample could be
attributed to demographic variations or treatment patterns, emphasizing the
need for additional study on medication management and outcomes in vertigo [39].
Table 7: Individual no.
of responses for question 4
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Have you
experienced any episodes of vertigo?
|
No of participants
|
Percentage
(%)
|
Mean +/- SD
|
|
Yes
|
356
|
30.90%
|
1.69 ± 0.46
|
|
No
|
796
|
69.09%
|
In our study, 30.90% of individuals reported having vertigo
episodes, whereas 69.09% did not. This is consistent with M von Brevern et al., who
discovered that 8% of people with moderate to severe vertigo met the criteria
for benign paroxysmal positional vertigo (BPPV), 24% had a history of
vestibular vertigo, and 2% experienced frequent vertigo triggered by head
movements despite not meeting BPPV criteria [40].
Table 8: Individual
no. of responses for question 5
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If yes, how often
do you experience vertigo episodes?
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No of participants
|
Percentage (%)
|
Mean +/- SD
|
|
Daily
|
100
|
8.68%
|
3.41 ± 0.998
|
|
Monthly
|
110
|
9.54%
|
|
Rarely
|
807
|
70.05%
|
|
Weekly
|
135
|
11.71%
|
In our study, 8.68% of patients had vertigo every day,
11.72% weekly, 9.55% monthly, and 70.05% seldom. Casani et al. looked at
249 patients divided by vertigo type and age, concentrating on clinical history
and demography. While Casani et al. focused on patient classification and age,
our study provides precise frequency data on vertigo episodes across multiple
age groups
[41].
Table 9: Individual no. of responses for
question 6
|
Describe the nature
of vertigo
|
No of participants
|
Percentage (%)
|
Mean +/- SD
|
|
Spinning Sensation
|
221
|
19.18%
|
2.81 ± 1.17
|
|
Light-headedness
|
264
|
22.91%
|
|
Feeling of balance
|
181
|
15.71%
|
|
Other
|
486
|
42.18%
|
In our study, 19.18% of individuals reported spinning
feelings, 22.91% light-headedness, 15.71% imbalance, and 42.18% additional
vertigo symptoms. R. Teggi et al. discovered 13.7% spinning
sensations, 26.3% relapsing episodes, 12.9% positional aggravation, and 4.8%
cochlear symptoms. Variations in symptom prevalence between studies may be due
to differences in demographics, methodologies, or diagnostic criteria [42].
Table 10: Individual no. of responses for
question 7
|
Duration of vertigo
|
No of participants
|
Percentage (%)
|
Mean +/- SD
|
|
Less than 1 minutes
|
619
|
53.73%
|
1.82 ± 1.05
|
|
1-5 minutes
|
271
|
23.52%
|
|
6-30 minutes
|
118
|
10.24%
|
|
More than 30 minutes
|
144
|
12.5%
|
In our study, 53.73% of individuals had vertigo for less than
one minute, 23.52% for one to five minutes, 10.24% for six to thirty
minutes,12.5% for more than thirty minutes, demonstrating that vertigo is often
brief but can linger longer in some situations. Li W, Cheng Y et al.'s
study of 76 patients focused on tumor location and operation type, providing a
unique clinical context unrelated to vertigo duration [43].
Table 11: Individual no. of responses for
question 8
|
Do you experience
any associated symptoms during episode
|
No. of participants
|
Percentage (%)
|
Mean +/- SD
|
|
Vomiting
|
170
|
14.75%
|
3.43 ± 1.51
|
|
Tinnitus (ringing in the ears)
|
174
|
15.10%
|
|
Headache
|
281
|
24.39%
|
|
Vomiting, Tinnitus
|
40
|
3.47%
|
|
Other
|
487
|
42.27%
|
In our study, 14.75% of patients reported vomiting, 15.10%
tinnitus, 24.39% headaches, 3.47% vomiting plus tinnitus, and 42.27% other
symptoms. Similarly, Magdalena
Nowaczewska et al. found that
49.3% of 286 tinnitus patients also had headaches, with this group being more
typically female, younger, and having greater rates of vertigo and depression.
Both studies emphasize the common coexistence of tinnitus and headaches, with
Nowaczewska delving deeper into associated clinical and demographic variables [44].
Table 12: Individual no. of responses for
question 9
|
What triggers your vertigo
episodes?
|
No. of participants
|
Percentage (%)
|
Mean +/- SD
|
|
Rapid head movements
|
149
|
12.93%
|
3.86 ± 1.65
|
|
Changes in positions
|
148
|
12.84%
|
|
Stress or anxiety
|
173
|
15.01%
|
|
Brightness or loud noise
|
84
|
7.29%
|
|
Others
|
442
|
38.36%
|
|
Multiple conditions
|
156
|
13.54%
|
Our study discovered that vertigo was caused by stress or
anxiety (15.02%), rapid head movements (12.93%), position changes (12.85%),
brightness or loud noise (7.29%), other factors (38.36%), and numerous triggers
(13.54%). These findings show that patients suffering with vestibular migraine
(VM) could benefit from targeted mobility, posture, and lifestyle guidance, Xiao BJ et al. back this up by focusing tailored instruction on stress
management, exercise, and lifestyle improvements to prevent VM recurrence and
enhance outcomes [45].
Table 13: Individual
no. of responses for question 10
|
Do you notice a
pattern or specific times when vertigo occurs
|
No of participants
|
Percentage (%)
|
Mean +/- SD
|
|
Yes
|
345
|
29.92%
|
0.299 ± 0.458
|
|
No
|
808
|
70.08%
|
Our study discovered that 29.92% of subjects observed a
pattern or specific times for vertigo attacks, whereas 70.08% did not. Ichijo H et al., on the other hand, found distinct time patterns, with
vertigo occurring during sleep, upon rising, in the morning, or afternoon in
various patient groups. This implies that, while some people experience
time-specific vertigo, many do not show apparent patterns [46].
Table 14: Individual no. of responses for
question 11
|
How does vertigo
impact your daily activities? (Rate from 1-5, where 1 = No impact, 5 = Severe
impact)
|
1
|
2
|
3
|
4
|
5
|
Mean +/- SD
|
|
Work/school
|
588
(51.04%)
|
195
(16.92%)
|
184
(15.97%)
|
108
(9.37%)
|
77
(6.68%)
|
2.14 ± 1.29
|
|
Social activities
|
453
(39.32%)
|
268
(23.26%)
|
273
(23.69%)
|
97
(8.42%)
|
61
(5.29%)
|
2.33
± 1.20
|
|
Physical activities
|
453
(39.32%)
|
268
(23.26%)
|
273
(23.69%)
|
97
(8.42%)
|
61
(5.29%)
|
2.33 ± 1.20
|
|
Daily tasks
|
494
(42.88%)
|
205
(17.79%)
|
237
(20.57%)
|
157
(13.62%)
|
38
(3.29%)
|
2.09
± 1.21
|
Our study of 1,152 individuals found that, while more
than half reported no effect of vertigo on work or school, a significant
proportion suffered moderate to severe effects on social activities, physical
exercise, and everyday tasks. Similarly, Ayse
Gunes-Bayir et al. discovered
that persons with vertigo were older, more likely to be overweight, and had
different food habits than controls. Together, these data emphasize vertigo's
major influence on daily living and the significance of addressing lifestyle
and nutritional aspects in its treatment [47].
Table 15: Individual no. of responses for
question 12
|
Have you sought
medical help for your vertigo
|
No of participants
|
Percentage (%)
|
Mean +/- SD
|
|
Yes
|
293
|
25.43
|
0.254 ± 0.435
|
|
No
|
859
|
74.56
|
Our study discovered that just 25.43% of participants sought
medical attention for vertigo, while 74.56% did not, showing that many people
shun professional aid. Similarly, Eva
Grill et al. found that even when
patients contact primary care, vertigo is frequently misdiagnosed or poorly
treated before being sent to specialists. These findings show considerable gaps
in vertigo management, including underutilization of medical resources and inadequate
primary care [48].
Table 16: Individual
no. of responses for question 13
|
If yes, what
treatments have you received?
|
No. of participants
|
Percentage (%)
|
Mean +/- SD
|
|
Medication
|
172
|
14.93%
|
5.41 ± 2.25
|
|
Physical therapy
|
146
|
12.67%
|
|
Vestibular rehabilitation
|
78
|
6.77%
|
|
All above 3 conditions.
|
84
|
7.29%
|
|
Others
|
84
|
7.29%
|
|
Other multiple options
|
588
|
51.04%
|
Despite strong recommendations for vestibular
rehabilitation and physical therapy to improve vestibular function, only 6.77%
and 12.67% of patients underwent them, respectively. Meanwhile, medication use
(14.93%) and other therapies (51.04%) were more prevalent, indicating
underutilization of rehabilitation. According to Courtney D. Hell et al.,
this disparity could be attributed to difficulties with guideline
implementation and awareness [49].
Table 17: Individual
no. of responses for question 14
|
Please provide any
additional information or comments
|
No of Participants
|
Percentage (%)
|
Mean +/- SD
|
|
Imbalance
|
62
|
5.38%
|
4.39 ± 1.07
|
|
Headache
|
27
|
2.34%
|
|
Stress
|
31
|
2.69%
|
|
Tinnitus
|
10
|
0.86%
|
|
Other
|
1022
|
88.71%
|
Regarding issue 14, 88.71% of participants provided
additional feedback, with 5.38% indicating unbalance, 2.34% headaches, 2.69%
tension, and 0.86% tinnitus. Unbalance was the most common complaint, but
headaches, stress, and tinnitus were all prevalent. These findings are
consistent with those of L. E. G. H. de
Joode et al., who identified
tinnitus, vertigo, and imbalance as typical vertigo symptoms and emphasized the
complexity and variety of vertigo episodes, which are frequently isolated and
include occasional visual auras [50].
Table 18: Individual no. of responses for
question 15
|
Do you consent to participate in this
study?
|
No of participants
|
Percentage (%)
|
Mean +/- SD
|
|
Yes
|
602
|
52.25%
|
0.522
± 0.499
|
|
No
|
550
|
47.74%
|
Individual no. of responses for
question 15 Depicts the information regarding the responses of number of
participants answered the 15th question according to the perceivance obtained
along with their respective percentages according to responses given by the
participants, the responses to the consent question show that 602 participants
(52.25%) consented to participate in the study, while 550 participants (47.74%)
did not consent.
Table 19: Individual
no. of responses for question 16 of vertigo symptoms scale
|
Vertigo
Symptoms Scale
|
0
|
1
|
2
|
3
|
4
|
5
|
Mean +/- SD
|
|
Spinning sensation
|
627
|
235
|
147
|
58
|
34
|
51
|
0.91+/-1.36
|
|
Light-headedness
|
467
|
364
|
170
|
69
|
52
|
30
|
1.12+/-1.28
|
|
Feeling of unsteadiness
|
485
|
275
|
218
|
92
|
41
|
41
|
1.15+/-1.35
|
|
Nausea
|
542
|
235
|
199
|
92
|
45
|
39
|
1.11+/-1.36
|
|
Vomiting
|
555
|
233
|
204
|
79
|
48
|
53
|
1.07+/-1.33
|
|
Tinnitus
|
570
|
248
|
184
|
71
|
35
|
44
|
1.03+/-1.33
|
|
Headache
|
447
|
308
|
212
|
87
|
55
|
43
|
1.24+/-1.36
|
|
Hearing loss
|
556
|
224
|
197
|
84
|
42
|
29
|
1.04+/-1.30
|
|
Difficulty concentrating
|
474
|
287
|
223
|
86
|
41
|
41
|
1.18+/-1.33
|
|
Anxiety
|
541
|
272
|
174
|
86
|
43
|
36
|
1.07+/-1.33
|
|
Fatigue
|
544
|
260
|
188
|
68
|
52
|
40
|
1.08+/-1.35
|
Participants'responses to the Vertigo Symptoms Scale (ranked
0–5 for severity) revealed that "no symptoms" was the most prevalent
response across all symptoms, including spinning sensation (54.5%), nausea
(47.2%), tinnitus (46.5%). Mild to moderate symptoms were reported by various
percentages of subjects, with fewer having severe to very severe symptoms. The
study divided participants into moderate (<24) and severe (≥24) vertigo
groups based on their cumulative symptom scores, which included spinning, light-headedness,
unsteadiness, nausea, vomiting, tinnitus, migraines, hearing loss, difficulties
concentrating, anxiety, and fatigue. Çakır
et al. found that vertigo can
have a considerable impact on health-related quality of life (HRQoL), even with
mild to moderate symptoms.
[51].
Table 20: Individual no. of responses for
question 17 of vertigo symptoms scale
|
Dizziness
handicapped inventory
|
0
|
1
|
2
|
Mean +/- SD
|
|
A. I feel unsteady when I walk in the
dark.
|
699
(60.67%)
|
276
(23.96%)
|
177
(15.37%)
|
0.55 ± 0.75
|
|
B. I have difficulty concentrating
because of my dizziness.
|
535
(46.44%)
|
464
(40.27%)
|
153
(13.28)
|
0.67
± 0.70
|
|
C. I avoid certain places because I
might get dizzy.
|
613
(53.21%)
|
331
(28.73%)
|
208
(18.05%)
|
0.65 ± 0.77
|
|
D. I get anxious when I think about
getting dizzy.
|
583
(50.06%)
|
361
(31.33%)
|
208
(18.05%)
|
0.67
± 0.76
|
|
E. I feel off-balance when I walk.
|
583
(50.06%)
|
368
(31.94%)
|
201
(17.44%)
|
0.67 ± 0.75
|
|
F. I feel frustrated by my dizziness.
|
592
(51.38%)
|
360
(31.52%)
|
200
(17.39%)
|
0.66
± 0.75
|
|
G. I have trouble getting up from a
seated position.
|
584
(50.7%)
|
343
(29.77%)
|
225
(19.53%)
|
0.69 ± 0.78
|
|
H. My dizziness interferes with my
social activities.
|
581
(50.43%)
|
381
(33.07%)
|
190
(16.50%)
|
0.66
± 0.74
|
|
I. I need help with everyday tasks
due to my dizziness.
|
625
(54.25%)
|
318
(27.60%)
|
209
(18.14%)
|
0.64 ± 0.77
|
|
J. I worry about falling because of
my dizziness.
|
580
(50.3%)
|
379
(32.90%)
|
193
(16.80%)
|
0.66
± 0.74
|
|
K. I feel tired because of my
dizziness.
|
584
(50.70%)
|
365
(31.68%)
|
203
(17.62%)
|
0.67 ± 0.76
|
|
L. I have trouble focusing on work
because of my dizziness.
|
578
(50.17%)
|
377
(32.72%)
|
197
(17.10%)
|
0.67
± 0.76
|
|
M. I avoid exercising because of my
dizziness.
|
611
(53.03%)
|
336
(29.16%)
|
205
(17.80%)
|
0.65 ± 0.77
|
|
N. I feel helpless when I have
dizziness.
|
594
(51.56%)
|
375
(32.55%)
|
183
(15.88%)
|
0.64
± 0.74
|
|
O. I have difficulty walking on
uneven surfaces.
|
603
(52.34%)
|
348
(30.20%)
|
201
(17.44%)
|
0.65 ± 0.76
|
The Dizziness Handicap Inventory (DHI) responses show that
dizziness has an impact on daily activities and mental health, with many
participants experiencing mild to severe difficulties in balance (e.g., 39.33%
reported mild/severe difficulty walking in the dark), concentration (53.55%),
anxiety (49.38%), and mobility (up to 37% difficulty with uneven surfaces). Schmid et
al. discovered considerable relationships between DHI scores and
psychological characteristics such as obsessiveness, phobic anxiety, and
quality of life, stressing the importance of emotional and functional
components in controlling dizziness.
[52].
OFFLINE DATA
Table 21: Age Vs No. of Subjects
|
S.
No
|
Age
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
3
4
5
6
7
8
|
18
19
20
21
22
23
24
25
|
142
103
109
86
44
17
9
8
|
27.41%
19.88%
21.04%
16.60%
8.49%
3.28%
1.73%
1.54%
|
20.8±1.91 years
|
Depicts the information regarding
the distribution of No of participants within the age groups of 18 Years to 25
years. Majority of the participants were found within the age of 18 years were
142(27.413%), followed by 19 years were 103 (19.88%), 20 years were 109
(21.042%), 21 years were 86(16.60%), 22 years were 44 (8.494%), 23 years were
17 (3.281%), 24 years were 9 (1.737%) and 25 years were 8 (1.544%).
Table 22: Gender Vs No: of subjects
|
S. no
|
Gender
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
|
Female
Male
|
281
237
|
54.24%
45.75%
|
0.457±0.498
|
Our study included 518 participants, with females accounting
for 54.25% (281) and males for 45.75% (237). In contrast, Michele Ori et al.'s
smaller research of 72 vestibular migraine patients found a significantly
larger female predominance (88.89% vs. 11.11% men). Ori et al.'s findings
show a considerable gender gap in vestibular migraine, whereas our bigger
sample provides a more comprehensive picture of gender distribution in the
general population [53].
Table 23: BMI Vs No. of subjects
|
S. No
|
BMI (Kg/M2)
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
3
4
5
6
|
Underweight: <18.5
Healthy weight: < 24.9
Overweight: < 29.
Class 1 obesity: <34.9
Class 2 obesity < 39.9
Class 3 obesity >40
|
92
298
93
25
9
1
|
17.76%
57.52%
17.95%
4.82%
1.73%
0.19%
|
20.84±4.13
|
Our study of 518 participants classified their BMI as
follows: 17.76% underweight (<18.5), 57.53% healthy weight (18.5-24.9),
17.95% overweight (25-29.9), 4.83% Class 1 obesity (30-34.9), 1.74% Class 2
obesity (35-39.9), and 0.19% Class 3 obesity (≥40). While our work gives a
comprehensive picture of BMI distribution in the general population, Dilek Baday-Keskin et al. conducted a smaller study that focused exclusively on
BMI's involvement in 31 patients with Benign Paroxysmal Positional Vertigo
(BPPV) and 30 controls, demonstrating its relevance to that condition. [54].
Table 24:
Individual no. of responses for Test 4
|
S. No
|
Pulse
(Beats/Minute)
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
3
4
5
|
40-50
60-80
80-90
90-100
100-110
|
2
112
201
125
78
|
0.38%
21.6%
38.8%
24.1%
15.0%
|
86.17±9.13
|
Our study of 518 participants discovered that the largest
group (201 individuals, 38.8%) had pulse rates between 80-90 bpm, followed by
125 (24.1%) at 90-100 bpm, 112 (21.6%) at 60-80 bpm, 78 (15.1%) at 100-110 bpm,
and only 2 (0.4%) at 40-50 bpm. In contrast, Serhat Günlü et al. analyzed heart rate variability in 70
vertigo patients, indicating that those with vertigo—especially with
arrhythmias—frequently exhibit considerable autonomic nervous system
dysfunction indicated by increased sympathetic activity, which can exacerbate upon
standing [55].
Table 25:
Individual no. of responses for Test 5
|
S. No
|
Blood Pressure
(mmHg)
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
|
100/60
100/70
100/80
100/90
110/80
110/60
110/70
110/80
110/90
120/60
120/70
120/80
120/90
130/70
130/80
130/90
140/100
140/70
140/80
140/90
150/70
|
9
7
4
2
1
10
146
47
1
2
53
136
5
18
47
21
2
1
4
1
1
|
1.73%
1.35%
0.77%
0.38%
0.19%
1.93%
28.18%
9.07%
0.19%
0.38%
10.23%
26.25%
0.96%
3.47%
9.07%
4.05%
0.38%
0.19%
0.77%
0.19%
0.19%
|
101.11± 14.59
|
Our study of 518 participants found that a large proportion
had normal blood pressure, with 28.18% at 110/70 mmHg and 26.25% at 120/80
mmHg. Elevated readings were uncommon, with 9.07% at 130/80 mmHg and 0.77% at
140/80 mmHg, while 1.74% had low-normal values such as 100/60 mmHg. These
findings are consistent with those of Moon-Jung
Kim et al., whose smaller study
found that the majority of participants' blood pressures were within a healthy
range, showing a broadly normal distribution across both investigations [56].
Table 26:
Individual No: of responses for Test 6
|
S. No
|
Head
Impulse Test
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
3
4
5
6
|
Bilateral
Bilateral>Left
Bilateral>Right
Left
Right
Normal
|
208
9
8
141
142
10
|
40.15%
1.73%
1.54%
27.22%
27.41%
1.93%
|
3.06 ±
1.78
|
Our three-month study of 518 participants found a significant
prevalence of vestibular dysfunction: 40.15% bilateral, 27.41% right-sided, and
27.22% left-sided, with just 1.93% having normal head impulse tests. Bilateral
dominance was shown in smaller amounts (1.74% left, 1.54% right). This big
sample provides a comprehensive overview of vestibular deficits. Paloma Eza-Nuñez et al.'s year-long study of 123 individuals offers deeper
long-term insights, but has limited generalizability due to its small size and
concentration on chronic patients. [57].
Table 27: Individual No. of responses for Test
7
|
S. No
|
Gait Test
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
3
4
5
6
|
Bilateral
Bilateral>Left
Bilateral>Right
Left
Right
Normal
|
119
4
12
210
172
1
|
22.97%
0.77%
2.31%
40.54%
33.20%
0.19%
|
3.61 ±
1.51
|
Our three-month study of 518 younger individuals discovered
that only 0.19% had a normal gait, whereas 40.54% had left-sided issues, 33.20%
right-sided issues, and 22.97% bilateral abnormalities. This focuses on gait
problems in young people. In contrast, Joe
Verghese et al.'s 20-month study of older adults found
that those with neurological gait problems had a higher fall rate (0.66 vs.
0.43 falls per person-year), emphasizing the long-term fall risk in older populations,
whereas our study focuses on short-term gait dysfunction in younger people [58].
Table 28:
Individual No. of responses for Test 8
|
S. No.
|
Romberg Test
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
3
4
|
Bilateral
Left
Right
Normal
|
133
208
176
1
|
25.67%
40.15%
33.97%
0.19%
|
2.09±0.77
|
Our
study of 518 participants discovered that more than 65% (208 people) had
balance problems on Romberg's test, with 40.15% having left-sided issues,
33.98% right-sided issues, and 25.68% bilateral problems. Santhosh kumar
Rajamani et.al.., Only 0.19%
demonstrated normal equilibrium. These results are consistent with the
comparator group, emphasizing the significant incidence of balance impairments,
particularly on the left side, as well as the rarity of normal balance among
individuals [59].
Table 29: Individual no: of responses for Test
9
|
S. No
|
Rotatory Chair Test
|
No. of Participants
|
Percentage
|
Mean ± SD
|
|
1
2
3
4
5
6
|
Bilateral
Bilateral>Left
Bilateral>Right
Left
Right
Normal
|
165
6
7
184
153
3
|
31.85%
1.15%
1.35%
35.52%
29.53%
0.57%
|
3.32±1.67
|
Our
study of 518 people utilizing rotatory chair tests found that vestibular
dysfunction mostly affected the left ear (35.52%), followed by bilateral issues
(31.85%) and right ear problems (29.52%), with only 0.58% demonstrating normal
vestibular function. This demonstrates the universality of vestibular
dysfunction on the ear side. In contrast, Mathias Winther Bech et al.'s
research of 281 patients highlighted the MRC test's diagnostic accuracy for
benign paroxysmal positional vertigo (BPPV), displaying high sensitivity (71%)
and specificity (98%). While our study examines the prevalence of vestibular
impairment, theirs assesses diagnostic precision for a specific ailment [60].
Table 30:
Individual no: of responses for Test 10
|
S. No
|
Finger-Nose Coordination
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
3
4
|
Bilateral
Left
Right
Normal
|
114
225
174
4
|
22.007%
43.436%
33.590%
0.772%
|
2.13±0.75
|
Our three-month study of 518 participants revealed that just
0.77% had normal finger-nose coordination, whereas 43.44% had difficulty with
the left hand, 33.59% with the right hand, and 22.01% had bilateral
coordination problems, indicating widespread motor coordination deficiencies.
In contrast, Kazuki Nishida et al.'s 12-month research of 357
people found a high (OR 22.6) link between poor finger-nose synchronization and
cerebrovascular events such as strokes and transient ischemic episodes. While
Nishida et al. emphasize the clinical significance of coordination deficiencies
as predictors of cerebrovascular risk, our study examines their frequency in
the general population [61].
Table 31:
Individual No. of responses for Test 11
|
S.
No
|
Skew Deviation Test
|
No. of Participants
|
Percentage (%)
|
Mean ± SD
|
|
1
2
3
4
5
6
|
Bilateral
Bilateral>Left
Bilateral>Right
Left
Right
Normal
|
33
0
1
233
195
56
|
6.37%
0
0.19%
44.98%
37.64%
10.81%
|
4.40±1.10.
|
Our
study of 518 participants found a high prevalence of skew deviation, with
44.98% showing left eye involvement, 37.64% right eye involvement, 10.81%
normal alignment, and 6.37% with moderate deviation. Compared to M. Chandrakumar et al.'s findings on posture-related changes that aid in
diagnosis, and Wong's emphasis on clinical differentiation, our data adds
valuable prevalence insight to the overall understanding of skew deviation. [62].
CONCLUSION
Given
the high prevalence of vertigo among young adults in the Amaravati Capital
Region and the importance of early diagnosis and comprehensive management, this
study's findings provide a solid basis for future research focusing on targeted
prevention, timely intervention, and effective therapeutic strategies to reduce
the burden of vertigo in this population. Clinical evaluations identified key
risk factors, such as lifestyle and environmental influences, and revealed
multiple underlying causes.
ABBREVIATIONS
BPPV: benign paroxysmal positional vertigo; SSCDS:
superior semicircular canal dehiscence syndrome; HINTS: Head impulse,
nystagmus, test of skew; VOR: vestibulo-ocular reflex; SCCs: semicircular
canals; DVA: Dynamic visual acuity; HIT: Head Impulse Test; OTR: Ocular Tilt
Reaction; SVV: Subjective Visual Vertical; SD: skew deviation; VN: vestibular
neuritis; SVN: superior vestibular nerve; SSRIs: selective serotonin reuptake
inhibitors; VM: vestibular migraine; HRV: heart rate variability; VDB:
vertigo dizziness, and balance disorders;
ACKNOWLEDGEMENTS
We
gratefully acknowledge our guide, Mr. Sreenu Thalla Associate Professor,
Department of Pharmacology, Vignan Pharmacy College and Dr. P. Srinivasa Babu,
Principal of Vignan Pharmacy College, Vadlamudi for ultimate support.
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