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Author(s): Sreenu Thalla1, * Bhukya Moshe Nayak. Jakkampudi Nikhitha2, Datla Bhavya Reddy3, Nemalikanti Viharika4, Puttagunta Srinivasa Babu5

Email(s): 1sreenuthalla87@gmail.com

Address:

    Vignan Pharmacy College (Autonomous), Vadlamudi, Guntur, Andhra Pradesh - 522213

Published In:   Volume - 5,      Issue - 7,     Year - 2026


Cite this article:
Sreenu Thalla. A Prospective Observational Study on the Clinical Evaluation of Vertigoin Young Adult Population of Amaravati Capital Region. IJRPAS, July 2026; 5(7): 174-196.

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A Prospective Observational Study on the Clinical Evaluation of Vertigoin Young Adult Population of Amaravati Capital Region

Sreenu Thalla,* Bhukya Moshe Nayak. Jakkampudi Nikhitha, Datla Bhavya Reddy, Nemalikanti Viharika, Puttagunta Srinivasa Babu

 

Vignan Pharmacy College (Autonomous), Vadlamudi, Guntur, Andhra Pradesh - 522213

*Correspondence: sreenuthalla87@gmail.com

DOI: https://doi.org/10.71431/IJRPAS.2026.5713          

Article Information

 

Abstract

Review Article

Received: 23/07/2026

Accepted: 26/07/2026

Published:31/07/2026

 

Keywords

Vertigo; BPPV; Amaravati;

 

Background: Vertigo, which is exacerbated by head movement, is the feeling of movement or spinning when none is happening. It is frequently accompanied by nausea, perspiration, or trouble walking.  It is the most prevalent type of vertigo and is frequently brought on by vestibular neuritis, Ménière's disease and benign paroxysmal positional vertigo (BPPV).  Stroke, brain tumors, multiple sclerosis, migraines, trauma and exposure to toxins are fewer common causes.  Unlike other forms of dizziness, such as presyncope or disequilibrium, vertigo typically indicates an issue with the vestibular system.  A prospective observational research design was used for the investigation.

Result: Vertigo in 1,670 young people was investigated in this 6-month research conducted in Amaravati.  Positional alterations were responsible for 45.8% of instances of dizziness and unsteadiness, which were prevalent (65.2%).  The most common causes were BPPV (37.9%) and vestibular migraine (25.6%).  Among the treatments were medicine (56.3%), lifestyle modifications (21.2%), and physical therapy (22.5%).  With 83.1% of patients reporting alleviation, physical therapy was quite successful in treating BPPV.  The study emphasizes how common vertigo is in young adults and the need for focused treatments as well as more investigation into long-term effects.

Conclusion: The high frequency of vertigo among young individuals in the Amaravati Capital Region emphasizes the importance of early diagnosis and complete treatment. This study highlights significant risk variables, including lifestyle and environmental factors, and lays the groundwork for future research into focused prevention, timely intervention, and effective treatment techniques..

INTRODUCTION:

Vertigo is the sensation of spinning or movement when none exists, often accompanied by nausea, vomiting, balance problems, typically worsened by head movements. It is classified into two types:  peripheral vertigo, caused by inner ear disorders such as benign paroxysmal positional vertigo (BPPV), Ménière’s disease, vestibular neuritis; and central vertigo. Peripheral vertigo is more common and frequently caused by disruptions in the vestibular system. BPPV, the most common cause of positional vertigo, results from displaced calcium crystals (otoconia) in the semicircular canals—most often the posterior canal—leading to brief spinning episodes during head movements [1]. Ménière’s disease causes recurrent vertigo, tinnitus, hearing loss, and ear fullness, affecting approximately 17–200 people per 100,000 worldwide; its causes may include viral infections, detached otoconia, or anatomical change[2] Vestibular neuritis is typically linked to viral infections or ischemia, causing inflammation and vestibular dysfunction [3].Central vertigo arises from lesions in the brainstem or cerebellum due to stroke, tumors, multiple sclerosis, or head injuries, with 30–65% of patients experiencing vertigo or imbalance [4]. Vestibular migraines, transient ischemic attacks, and vascular conditions such as hypertension, atherosclerosis, embolism, and aneurysms can also cause central vertigo[5][6].Other causes include vestibular schwannomas, benign tumors of the vestibular nerve that cause unilateral vertigo, hearing loss, and tinnitus [7]. Superior semicircular canal dehiscence syndrome (SSCDS) caused by a bony defect producing abnormal responses to loud sounds or pressure. Chronic dizziness—a persistent, non-rotational sense of unsteadiness often worsened in visually complex environments[8].Accurate diagnosis, often using the HINTS exam, is essential to differentiate between peripheral and central vertigo [9].Dizziness, which includes symptoms like light-headedness, unsteadiness, and presyncope, lacks a precise definition and may stem from peripheral or central vestibular causes [10]. Diagnostic accuracy improves by focusing on symptom timing, triggers, and using the HINTS exam, which can outperform early neuroimaging in AVS cases [11]. BPPV is the most common cause, especially in older adults, with posterior canal BPPV accounting for over 80% of cases [12]. Other causes include vestibular neuritis, labyrinthitis (viral or bacterial) vestibular migraine and Meniere’s disease, which causes vertigo, tinnitus, and fluctuating hearing loss. Peri lymphatic fistula may result from trauma or surgery and presents with dizziness triggered by pressure or sound (Hennebert's, Tullio's signs) [13]. Patients with vertigo/dizziness have a significantly higher risk of stroke or cardiovascular events[14].BPPV prevalence rises with age, being seven times higher in those over 60 [15]. Vertigo can be triggered by head movements and postures, with shifting positions being the most common cause, affecting about half of individuals during standing or walking [16]. Complications of otitis media can lead to facial paralysis, labyrinthitis, and chronic ear infections [17]. Labyrinthitis can result from infections spreading from the middle ear, causing severe vertigo, nausea, and hearing loss, and in chronic cases, leading to labyrinthine ossification [18]. Comorbidities such as diabetes, hypertension, osteoporosis, and depression are commonly seen in older adults with BPPV [19]. These findings highlight the complex relationship between vertigo, comorbidities, and its increased prevalence with age.The rotatory chair test, a less commonly used vestibular function test, is valuable for measuring the vestibulo-ocular reflex (VOR), particularly in cases of bilateral vestibular hypofunction. It simulates the natural push-pull characteristics of the horizontal semicircular canals (SCCs) and generates nystagmus in most individuals, with only those with profound bilateral vestibular hypofunction showing no nystagmus. Dynamic visual acuity (DVA) tests evaluate VOR by assessing gaze stability during head motion [20]. The Head Impulse Test (HIT) can be used at the bedside to assess VOR, although it has limitations in sensitivity and specificity Pathological HIT is typically associated with peripheral vestibular lesions but may also occur in certain central lesions, such as strokes [21]. Ocular Tilt Reaction (OTR) and Subjective Visual Vertical (SVV) tests are used to differentiate between central and peripheral vestibular dysfunction, with pronounced skew deviation (SD) [22].Romberg, Jendrassik, and balance tests like Single Leg Stance, Tandem Gait, and the Timed Up and Go test further assess stability, with positive tests indicating vestibular dysfunction. For instance, in Romberg testing, the Jendrassik maneuver increases test difficulty, and a test is positive if the subject moves before 30 seconds. In the Single Leg Stance test, the subject must maintain balance with eyes open or closed for up to 30 seconds. The Tandem Gait test requires walking heel-to-toe for 20 steps, and the Timed Up and Go test measures the time it takes to rise, walk 3 meters, turn, and return to the chair. These tests are vital for diagnosing vestibular issues and evaluating the severity of dysfunction [23].

 Vertigo treatment primarily involves vestibular suppressants and antiemetics. Anticholinergics like scopolamine reduce nystagmus [24]. Antihistamines help prevent motion sickness and vertigo symptoms but have side effects [25]. Benzodiazepines, such as lorazepam, are effective at low doses but can cause habituation and memory issues[26]. Calcium channel antagonists, like cinnarizine, are used in Meniere’s disease but are not universally accepted [27]. Antiemetics, such as meclizine, treat nausea, while dopamine antagonists like prochlorperazine are second-line due to side effects[28].For BPPV, physical therapy is the primary treatment, with meclizine helping with nausea [29].In Meniere’s disease, vestibular suppressants manage acute attacks, while salt restriction and diuretics may reduce attacks [30]. Vestibular neuritis is managed with minimal medication and activity encouragement to aid recovery [31]. Bilateral vestibular paresis is typically caused by ototoxic antibiotics like gentamicin following infections such as osteomyelitis or peritonitis. [32]. Central vertigo, a rarer cause (5% of cases in ER settings), is mainly due to vascular disorders like stroke or migraine, with prolonged symptoms. Common treatments include verapamil, amitriptyline, and benzodiazepines. For migraine-related vertigo, SSRIs and β-blockers can also be used. In patients with known CNS lesions, benzodiazepines like lorazepam and prochlorperazine may help. Gabapentin, carbamazepine, or acetazolamide may be used for specific vertigo conditions [33]. Psychogenic vertigo, linked to psychiatric disorders such as anxiety or depression, is treated with psychiatric interventions. Benzodiazepines are effective for anxiety, while SSRIs may help with depression. In cases of somatization or malingering, no medication is prescribed, but reducing unnecessary healthcare usage is the goal [34]. When the cause of vertigo is undetermined, the treatment is empirical, often involving a medication withdrawal strategy and trials of meclizine, clonazepam, or migraine treatments like verapamil. Monitoring is essential, as conditions like Meniere’s disease or acoustic neuromas may evolve over time [35].

METHODOLOGY

STUDY DESIGN: It is a prospective observational study

STUDY PERIOD: The study was conducted for 6 months (July 2024 to December 2024).

STUDY METHOD: This study was conducted in Vignan Pharmacy College, Vadlamudi, Guntur. This study involves all the subjects who were included in the inclusion and exclusion criteria. Subjects are observed for their provoking factors, incidence and prevalence of emergency cases. An informed consent form will be taken from the participant.

SAMPLE SIZE: 518 (offline) and 1152 (online) young adults.

STUDY MATERIALS: Patient data collection form, Patient consent form

STATISTICAL ANALYSIS: The obtained data was statistically analysed and the results were represented by using SPSS Software Version 23.0.

INCLUSION CRITERIA: Patients aged 18 years and above, Patients who provide informed consent to participate in the study.
EXCLUSION CRITERIA: Patients with incomplete medical records, Inability to provide informed
 consent, psychologically disabled patient.

RESULTS & DISCUSSIONS

For Online Data

Table 1: Age Vs No. of Participants

Age

No. of Participants

Percentage (%)

Mean +/- SD

18

370

32.11%

 

 

 

22.3 ± 3.35 years

19

224

19.44%

20

190

16.49%

21

153

13.28%

22

90

7.81%

23

68

5.90%

24

24

2.08%

25

33

2.86%

Depicts the information regarding the distribution of study subjects within the age groups of 18 years to 25 years. Majority of the subjects were found within the age of 18 years (32.11%), followed by 19 years (19.44%), 20 years (16.49%), 21 years (13.28%), 22 years (7.81%), 23 years (5.90%), 24 years (2.08%) and 25 years (2.86%).

 

 

 

Table 2: Gender Vs No. of Participants

Gender

No. of participants

Percentage (%)

Mean+/-SD

Male

627

54.16%

1.46 ± 0.50

Female

525

45.57%

 

 

 

 

 

Comprising 525 women (45.57%) and 627 men (54.17%), the study had an average age of 1.46 ± 0.50 years. With an average vertigo annoyance score of 2.42, which indicates considerable discomfort, Hackenberg et al.'s study of 8,519 individuals, on the other hand, revealed a vertigo prevalence of 21.6%, peaking in the 55–64 age range. These findings imply that the occurrence and effects of vertigo differ considerably by demographic and age [36].

Table 3: Level of Education Vs No. of Participants

Level of Education

No. of participants

Percentage

Mean +/- SD

High School

59

5.121%

 

 

2.23 ± 0.59

Undergraduate

811

70.39%

Graduate

242

21.00%

Other

40

3.47%

 

 

 

 

 

 

Depicts the information regarding the level of education of the participants from high school to graduates and others. Majority of the participants were found as under graduates (70.39%), followed by high school (5.121%), graduates (21.006%) and others (3.472%).

Table 4: Individual no. of responses for question 1

Do you have any known medical condition

No. of participants

Percentage (%)

Mean  +/- SD

Yes

361

31.33%

 

1.69 ± 0.46

No

792

68.75%

 

 

 

 

 

In our survey of 1,153 people, 31.33% reported having a recognized medical condition, whereas 68.75% did not. Similarly, Sreenivas V et al. discovered that 45.1% of patients had hypertension, with hypertensive patients having greater recurrence rates (38.1%) than non-hypertensive patients (16%), implying a possible relationship between hypertension and recurrence [37].

 

 

 

 

Table 5: Individual no. of responses for question 2

Have you had any of the following in the past?

No. of participants

Percentage (%)

Mean +/- SD

Migraines

160

13.88%

 

 

 

4.35 ± 1.62

Ear infection

99

8.59%

Neurological disorder

31

2.69%

Head trauma

73

6.33%

others

664

57.63%

Multiple conditions

125

10.85%

Participants in our study reported migraines (13.88%), ear infections (8.59%), neurological illnesses (2.69%), head injuries (6.33%), others (57.68%), and multiple conditions (10.85%). These findings are consistent with Marcello Cherchi et al., who connected vestibular migraine (VM) to otologic diseases, and Faith W. Akin et al., who discovered that many patients with Meniere's disease also fit migraine criteria. The presence of numerous illnesses emphasizes the intricate link between VM and other medical concerns [38].

Table 6: Individual no. of responses for question 3

Are you currently taking any medications?

No of Participants

Percentage (%)

Mean +/- Standard Deviation

Yes

240

20.83%

1.79 ± 0.41

No

912

79.16%

 

In our survey, 20.83% of individuals said they took drugs, whereas 79.16% didn't. In contrast, Benedict Katzenberger et al. discovered that 35% of 158 patients with vertigo and balance difficulties were taking anticholinergic or sedative drugs, which were connected to impaired functioning. The reduced medication use in our younger sample could be attributed to demographic variations or treatment patterns, emphasizing the need for additional study on medication management and outcomes in vertigo [39].

Table 7: Individual no. of responses for question 4

Have you experienced any episodes of vertigo?

No of participants

Percentage

(%)

Mean +/- SD

Yes

356

30.90%

 

1.69 ± 0.46

No

796

69.09%

In our study, 30.90% of individuals reported having vertigo episodes, whereas 69.09% did not. This is consistent with M von Brevern et al., who discovered that 8% of people with moderate to severe vertigo met the criteria for benign paroxysmal positional vertigo (BPPV), 24% had a history of vestibular vertigo, and 2% experienced frequent vertigo triggered by head movements despite not meeting BPPV criteria [40].

Table 8: Individual no. of responses for question 5

If yes, how often do you experience vertigo episodes?

No of participants

Percentage (%)

Mean +/- SD

Daily

100

8.68%

3.41 ± 0.998

Monthly

110

9.54%

Rarely

807

70.05%

Weekly

135

11.71%

 In our study, 8.68% of patients had vertigo every day, 11.72% weekly, 9.55% monthly, and 70.05% seldom. Casani et al. looked at 249 patients divided by vertigo type and age, concentrating on clinical history and demography. While Casani et al. focused on patient classification and age, our study provides precise frequency data on vertigo episodes across multiple age groups [41].

Table 9: Individual no. of responses for question 6

Describe the nature of vertigo

No of participants

Percentage (%)

Mean +/- SD

Spinning Sensation

221

19.18%

 

 

2.81 ± 1.17

Light-headedness

264

22.91%

Feeling of balance

181

15.71%

Other

486

42.18%

 In our study, 19.18% of individuals reported spinning feelings, 22.91% light-headedness, 15.71% imbalance, and 42.18% additional vertigo symptoms. R. Teggi et al. discovered 13.7% spinning sensations, 26.3% relapsing episodes, 12.9% positional aggravation, and 4.8% cochlear symptoms. Variations in symptom prevalence between studies may be due to differences in demographics, methodologies, or diagnostic criteria [42].

Table 10: Individual no. of responses for question 7

Duration of vertigo

No of participants

Percentage (%)

Mean +/- SD

Less than 1 minutes

619

53.73%

 

 

1.82 ± 1.05

1-5 minutes

271

23.52%

6-30 minutes

118

10.24%

More than 30 minutes

144

12.5%

In our study, 53.73% of individuals had vertigo for less than one minute, 23.52% for one to five minutes, 10.24% for six to thirty minutes,12.5% for more than thirty minutes, demonstrating that vertigo is often brief but can linger longer in some situations. Li W, Cheng Y et al.'s study of 76 patients focused on tumor location and operation type, providing a unique clinical context unrelated to vertigo duration [43].

 

Table 11: Individual no. of responses for question 8

Do you experience any associated symptoms during episode

No. of participants

Percentage (%)

Mean +/- SD

Vomiting

170

14.75%

 

 

 

 

3.43 ± 1.51

Tinnitus (ringing in the ears)

174

15.10%

Headache

281

24.39%

Vomiting, Tinnitus

40

3.47%

Other

487

42.27%

In our study, 14.75% of patients reported vomiting, 15.10% tinnitus, 24.39% headaches, 3.47% vomiting plus tinnitus, and 42.27% other symptoms. Similarly, Magdalena Nowaczewska et al. found that 49.3% of 286 tinnitus patients also had headaches, with this group being more typically female, younger, and having greater rates of vertigo and depression. Both studies emphasize the common coexistence of tinnitus and headaches, with Nowaczewska delving deeper into associated clinical and demographic variables [44].

Table 12: Individual no. of responses for question 9

What triggers your vertigo episodes?

No. of participants

Percentage (%)

Mean +/- SD

Rapid head movements

149

12.93%

 

 

 

3.86 ± 1.65

Changes in positions

148

12.84%

Stress or anxiety

173

15.01%

Brightness or loud noise

84

7.29%

Others

442

38.36%

Multiple conditions

156

13.54%

Our study discovered that vertigo was caused by stress or anxiety (15.02%), rapid head movements (12.93%), position changes (12.85%), brightness or loud noise (7.29%), other factors (38.36%), and numerous triggers (13.54%). These findings show that patients suffering with vestibular migraine (VM) could benefit from targeted mobility, posture, and lifestyle guidance, Xiao BJ et al. back this up by focusing tailored instruction on stress management, exercise, and lifestyle improvements to prevent VM recurrence and enhance outcomes [45].

Table 13: Individual no. of responses for question 10

Do you notice a pattern or specific times when vertigo occurs

No of participants

Percentage (%)

Mean +/- SD

Yes

345

29.92%

0.299 ± 0.458

No

808

70.08%

Our study discovered that 29.92% of subjects observed a pattern or specific times for vertigo attacks, whereas 70.08% did not. Ichijo H et al., on the other hand, found distinct time patterns, with vertigo occurring during sleep, upon rising, in the morning, or afternoon in various patient groups. This implies that, while some people experience time-specific vertigo, many do not show apparent patterns [46].

Table 14: Individual no. of responses for question 11

How does vertigo impact your daily activities? (Rate from 1-5, where 1 = No impact, 5 = Severe impact)

1

2

3

4

5

Mean +/- SD

Work/school

588

(51.04%)

195

(16.92%)

184

(15.97%)

108

(9.37%)

77

(6.68%)

2.14 ± 1.29

Social activities

453

(39.32%)

268

(23.26%)

273

(23.69%)

97

(8.42%)

61

(5.29%)

2.33 ± 1.20

Physical activities

453

(39.32%)

268

(23.26%)

273

(23.69%)

97

(8.42%)

61

(5.29%)

2.33 ± 1.20

Daily tasks

494

(42.88%)

205

(17.79%)

237

(20.57%)

157

(13.62%)

38

(3.29%)

2.09 ± 1.21

 Our study of 1,152 individuals found that, while more than half reported no effect of vertigo on work or school, a significant proportion suffered moderate to severe effects on social activities, physical exercise, and everyday tasks. Similarly, Ayse Gunes-Bayir et al. discovered that persons with vertigo were older, more likely to be overweight, and had different food habits than controls. Together, these data emphasize vertigo's major influence on daily living and the significance of addressing lifestyle and nutritional aspects in its treatment  [47].

Table 15: Individual no. of responses for question 12

Have you sought medical help for your vertigo

No of participants

Percentage (%)

Mean +/- SD

Yes

293

25.43

0.254 ± 0.435

No

859

74.56

Our study discovered that just 25.43% of participants sought medical attention for vertigo, while 74.56% did not, showing that many people shun professional aid. Similarly, Eva Grill et al. found that even when patients contact primary care, vertigo is frequently misdiagnosed or poorly treated before being sent to specialists. These findings show considerable gaps in vertigo management, including underutilization of medical resources and inadequate primary care [48].

Table 16: Individual no. of responses for question 13

If yes, what treatments have you received?

No. of participants

Percentage (%)

Mean +/- SD

Medication

172

14.93%

 

 

 

 

5.41 ± 2.25

Physical therapy

146

12.67%

Vestibular rehabilitation

78

6.77%

All above 3 conditions.

84

7.29%

Others

84

7.29%

Other multiple options

588

51.04%

 Despite strong recommendations for vestibular rehabilitation and physical therapy to improve vestibular function, only 6.77% and 12.67% of patients underwent them, respectively. Meanwhile, medication use (14.93%) and other therapies (51.04%) were more prevalent, indicating underutilization of rehabilitation. According to Courtney D. Hell et al., this disparity could be attributed to difficulties with guideline implementation and awareness [49].

Table 17: Individual no. of responses for question 14

Please provide any additional information or comments

No of Participants

Percentage (%)

Mean +/- SD

Imbalance

62

5.38%

 

 

4.39 ± 1.07

Headache

27

2.34%

Stress

31

2.69%

Tinnitus

10

0.86%

Other

1022

88.71%

 Regarding issue 14, 88.71% of participants provided additional feedback, with 5.38% indicating unbalance, 2.34% headaches, 2.69% tension, and 0.86% tinnitus. Unbalance was the most common complaint, but headaches, stress, and tinnitus were all prevalent. These findings are consistent with those of L. E. G. H. de Joode et al., who identified tinnitus, vertigo, and imbalance as typical vertigo symptoms and emphasized the complexity and variety of vertigo episodes, which are frequently isolated and include occasional visual auras [50].

Table 18: Individual no. of responses for question 15

Do you consent to participate in this study? 

No of participants

Percentage (%)

Mean +/- SD

Yes

602

52.25%

0.522 ± 0.499

No

550

47.74%

 

 

 

 

 

Individual no. of responses for question 15 Depicts the information regarding the responses of number of participants answered the 15th question according to the perceivance obtained along with their respective percentages according to responses given by the participants, the responses to the consent question show that 602 participants (52.25%) consented to participate in the study, while 550 participants (47.74%) did not consent.

 

Table 19: Individual no. of responses for question 16 of vertigo symptoms scale

Vertigo

Symptoms Scale

0

1

2

3

4

5

Mean +/- SD

Spinning sensation

627

235

147

58

34

51

0.91+/-1.36

Light-headedness

467

364

170

69

52

30

1.12+/-1.28

Feeling of unsteadiness

485

275

218

92

41

41

1.15+/-1.35

Nausea

542

235

199

92

45

39

1.11+/-1.36

Vomiting

555

233

204

79

48

53

1.07+/-1.33

Tinnitus

570

248

184

71

35

44

1.03+/-1.33

Headache

447

308

212

87

55

43

1.24+/-1.36

Hearing loss

556

224

197

84

42

29

1.04+/-1.30

Difficulty concentrating

474

287

223

86

41

41

1.18+/-1.33

Anxiety

541

272

174

86

43

36

1.07+/-1.33

Fatigue

544

260

188

68

52

40

1.08+/-1.35

 

Participants'responses to the Vertigo Symptoms Scale (ranked 0–5 for severity) revealed that "no symptoms" was the most prevalent response across all symptoms, including spinning sensation (54.5%), nausea (47.2%), tinnitus (46.5%). Mild to moderate symptoms were reported by various percentages of subjects, with fewer having severe to very severe symptoms. The study divided participants into moderate (<24) and severe (≥24) vertigo groups based on their cumulative symptom scores, which included spinning, light-headedness, unsteadiness, nausea, vomiting, tinnitus, migraines, hearing loss, difficulties concentrating, anxiety, and fatigue. Çakır et al. found that vertigo can have a considerable impact on health-related quality of life (HRQoL), even with mild to moderate symptoms. [51].

Table 20: Individual no. of responses for question 17 of vertigo symptoms scale

Dizziness handicapped inventory

0

1

2

Mean +/- SD

A.     I feel unsteady when I walk in the dark.

699

(60.67%)

276

(23.96%)

177

(15.37%)

 

0.55 ± 0.75

B.     I have difficulty concentrating because of my dizziness.

535

(46.44%)

464

(40.27%)

153

(13.28)

 

0.67 ± 0.70

C.     I avoid certain places because I might get dizzy.

613

(53.21%)

331

(28.73%)

208

(18.05%)

0.65 ± 0.77

D.     I get anxious when I think about getting dizzy.

583

(50.06%)

361

(31.33%)

208

(18.05%)

 

0.67 ± 0.76

E.     I feel off-balance when I walk.

583

(50.06%)

368

(31.94%)

201

(17.44%)

 

0.67 ± 0.75

F.      I feel frustrated by my dizziness.

592

(51.38%)

360

(31.52%)

200

(17.39%)

 

0.66 ± 0.75

G.    I have trouble getting up from a seated position.

584

(50.7%)

343

(29.77%)

225

(19.53%)

 

0.69 ± 0.78

H.    My dizziness interferes with my social activities.

581

(50.43%)

381

(33.07%)

190

(16.50%)

 

0.66 ± 0.74

I.       I need help with everyday tasks due to my dizziness.

625

(54.25%)

318

(27.60%)

209

(18.14%)

 

0.64 ± 0.77

J.      I worry about falling because of my dizziness.

580

(50.3%)

379

(32.90%)

193

(16.80%)

 

0.66 ± 0.74

K.    I feel tired because of my dizziness.

584

(50.70%)

365

(31.68%)

203

(17.62%)

 

0.67 ± 0.76

L.     I have trouble focusing on work because of my dizziness.

578

(50.17%)

377

(32.72%)

197

(17.10%)

 

0.67 ± 0.76

M.   I avoid exercising because of my dizziness.

611

(53.03%)

336

(29.16%)

205

(17.80%)

 

0.65 ± 0.77

N.     I feel helpless when I have dizziness.

594

(51.56%)

375

(32.55%)

183

(15.88%)

 

0.64 ± 0.74

O.    I have difficulty walking on uneven surfaces.

603

(52.34%)

348

(30.20%)

201

(17.44%)

 

0.65 ± 0.76

The Dizziness Handicap Inventory (DHI) responses show that dizziness has an impact on daily activities and mental health, with many participants experiencing mild to severe difficulties in balance (e.g., 39.33% reported mild/severe difficulty walking in the dark), concentration (53.55%), anxiety (49.38%), and mobility (up to 37% difficulty with uneven surfaces). Schmid et al. discovered considerable relationships between DHI scores and psychological characteristics such as obsessiveness, phobic anxiety, and quality of life, stressing the importance of emotional and functional components in controlling dizziness. [52].

 

 

 

 

 

 

OFFLINE DATA

Table 21: Age Vs No. of Subjects

S. No

Age

No. of Participants

Percentage (%)

Mean ± SD

1

2

3

4

5

6

7

8

18

19

20

21

22

23

24

25

142

103

109

86

44

17

9

8

27.41%

19.88%

21.04%

16.60%

8.49%

3.28%

1.73%

1.54%

 

 

 

20.8±1.91 years

Depicts the information regarding the distribution of No of participants within the age groups of 18 Years to 25 years. Majority of the participants were found within the age of 18 years were 142(27.413%), followed by 19 years were 103 (19.88%), 20 years were 109 (21.042%), 21 years were 86(16.60%), 22 years were 44 (8.494%), 23 years were 17 (3.281%), 24 years were 9 (1.737%) and 25 years were 8 (1.544%).

Table 22: Gender Vs No: of subjects

S. no

Gender

No. of Participants

Percentage (%)

Mean ± SD

1

2

Female

Male

281

237

54.24%

45.75%

0.457±0.498

 

Our study included 518 participants, with females accounting for 54.25% (281) and males for 45.75% (237). In contrast, Michele Ori et al.'s smaller research of 72 vestibular migraine patients found a significantly larger female predominance (88.89% vs. 11.11% men). Ori et al.'s findings show a considerable gender gap in vestibular migraine, whereas our bigger sample provides a more comprehensive picture of gender distribution in the general population [53].

Table 23: BMI Vs No. of subjects

S. No

BMI (Kg/M2)

No. of Participants

Percentage (%)

Mean ± SD

1

2

3

4

5

6

Underweight:  <18.5

Healthy weight: < 24.9

Overweight: < 29.

Class 1 obesity: <34.9

Class 2 obesity < 39.9

Class 3 obesity >40

92

298

93

25

9

1

17.76%

57.52%

17.95%

4.82%

1.73%

0.19%

 

20.84±4.13

Our study of 518 participants classified their BMI as follows: 17.76% underweight (<18.5), 57.53% healthy weight (18.5-24.9), 17.95% overweight (25-29.9), 4.83% Class 1 obesity (30-34.9), 1.74% Class 2 obesity (35-39.9), and 0.19% Class 3 obesity (≥40). While our work gives a comprehensive picture of BMI distribution in the general population, Dilek Baday-Keskin et al. conducted a smaller study that focused exclusively on BMI's involvement in 31 patients with Benign Paroxysmal Positional Vertigo (BPPV) and 30 controls, demonstrating its relevance to that condition. [54].

Table 24:  Individual no. of responses for Test 4

S. No

Pulse (Beats/Minute)

No. of Participants

Percentage (%)

Mean ± SD

1

2

3

4

5

40-50

60-80

80-90

90-100

 100-110

2

112

201

125

78

0.38%

21.6%

38.8%

24.1%

15.0%

 

 

86.17±9.13

 

Our study of 518 participants discovered that the largest group (201 individuals, 38.8%) had pulse rates between 80-90 bpm, followed by 125 (24.1%) at 90-100 bpm, 112 (21.6%) at 60-80 bpm, 78 (15.1%) at 100-110 bpm, and only 2 (0.4%) at 40-50 bpm. In contrast, Serhat Günlü et al. analyzed heart rate variability in 70 vertigo patients, indicating that those with vertigo—especially with arrhythmias—frequently exhibit considerable autonomic nervous system dysfunction indicated by increased sympathetic activity, which can exacerbate upon standing [55].

Table 25:  Individual no. of responses for Test 5

S. No

Blood Pressure (mmHg)

No. of Participants

Percentage (%)

Mean ± SD

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

20

21

100/60

100/70

100/80

100/90

110/80

110/60

110/70

110/80

110/90

120/60

120/70

120/80

120/90

130/70

130/80

130/90

140/100

140/70

140/80

140/90

150/70

9

7

4

2

1

10

146

47

1

2

53

136

5

18

47

21

2

1

4

1

1

1.73%

1.35%

0.77%

0.38%

0.19%

1.93%

28.18%

9.07%

0.19%

0.38%

10.23%

26.25%

0.96%

3.47%

9.07%

4.05%

0.38%

0.19%

0.77%

0.19%

0.19%

 

 

 

 

 

 

 

 

 

101.11± 14.59

Our study of 518 participants found that a large proportion had normal blood pressure, with 28.18% at 110/70 mmHg and 26.25% at 120/80 mmHg. Elevated readings were uncommon, with 9.07% at 130/80 mmHg and 0.77% at 140/80 mmHg, while 1.74% had low-normal values such as 100/60 mmHg. These findings are consistent with those of Moon-Jung Kim et al., whose smaller study found that the majority of participants' blood pressures were within a healthy range, showing a broadly normal distribution across both investigations [56].

Table 26:  Individual No: of responses for Test 6

S. No

Head Impulse Test

No. of Participants

Percentage (%)

Mean ± SD

1

2

3

4

5

6

Bilateral

Bilateral>Left

Bilateral>Right

Left

Right

Normal

208

9

8

141

142

10

40.15%

1.73%

1.54%

27.22%

27.41%

1.93%

 

 

 

3.06 ± 1.78

Our three-month study of 518 participants found a significant prevalence of vestibular dysfunction: 40.15% bilateral, 27.41% right-sided, and 27.22% left-sided, with just 1.93% having normal head impulse tests. Bilateral dominance was shown in smaller amounts (1.74% left, 1.54% right). This big sample provides a comprehensive overview of vestibular deficits. Paloma Eza-Nuñez et al.'s year-long study of 123 individuals offers deeper long-term insights, but has limited generalizability due to its small size and concentration on chronic patients. [57].

Table 27: Individual No. of responses for Test 7

S. No

Gait Test

No. of Participants

Percentage (%)

Mean ± SD

1

2

3

4

5

6

Bilateral

Bilateral>Left

Bilateral>Right

Left

Right

Normal

119

4

12

210

172

1

22.97%

0.77%

2.31%

40.54%

33.20%

0.19%

 

 

3.61 ± 1.51

 

Our three-month study of 518 younger individuals discovered that only 0.19% had a normal gait, whereas 40.54% had left-sided issues, 33.20% right-sided issues, and 22.97% bilateral abnormalities. This focuses on gait problems in young people. In contrast, Joe Verghese et al.'s 20-month study of older adults found that those with neurological gait problems had a higher fall rate (0.66 vs. 0.43 falls per person-year), emphasizing the long-term fall risk in older populations, whereas our study focuses on short-term gait dysfunction in younger people [58].

Table 28:  Individual No. of responses for Test 8

S. No.

Romberg Test

No. of Participants

Percentage (%)

Mean ± SD

1

2

3

4

Bilateral

Left

Right

Normal

133

208

176

1

25.67%

40.15%

33.97%

0.19%

 

2.09±0.77

  Our study of 518 participants discovered that more than 65% (208 people) had balance problems on Romberg's test, with 40.15% having left-sided issues, 33.98% right-sided issues, and 25.68% bilateral problems. Santhosh kumar Rajamani et.al.., Only 0.19% demonstrated normal equilibrium. These results are consistent with the comparator group, emphasizing the significant incidence of balance impairments, particularly on the left side, as well as the rarity of normal balance among individuals [59].

Table 29: Individual no: of responses for Test 9

S. No

Rotatory Chair Test

No. of Participants

Percentage

Mean ± SD

1

2

3

4

5

6

Bilateral

Bilateral>Left

Bilateral>Right

Left

Right

Normal

165

6

7

184

153

3

31.85%

1.15%

1.35%

35.52%

29.53%

0.57%

 

 

3.32±1.67

 

 Our study of 518 people utilizing rotatory chair tests found that vestibular dysfunction mostly affected the left ear (35.52%), followed by bilateral issues (31.85%) and right ear problems (29.52%), with only 0.58% demonstrating normal vestibular function. This demonstrates the universality of vestibular dysfunction on the ear side. In contrast, Mathias Winther Bech et al.'s research of 281 patients highlighted the MRC test's diagnostic accuracy for benign paroxysmal positional vertigo (BPPV), displaying high sensitivity (71%) and specificity (98%). While our study examines the prevalence of vestibular impairment, theirs assesses diagnostic precision for a specific ailment [60].

 

 

 

 

Table 30:  Individual no: of responses for Test 10

S. No

Finger-Nose Coordination

No. of Participants

Percentage (%)

Mean ± SD

1

2

3

4

Bilateral

Left

Right

Normal

114

225

174

4

22.007%

43.436%

33.590%

0.772%

 

2.13±0.75

 

Our three-month study of 518 participants revealed that just 0.77% had normal finger-nose coordination, whereas 43.44% had difficulty with the left hand, 33.59% with the right hand, and 22.01% had bilateral coordination problems, indicating widespread motor coordination deficiencies. In contrast, Kazuki Nishida et al.'s 12-month research of 357 people found a high (OR 22.6) link between poor finger-nose synchronization and cerebrovascular events such as strokes and transient ischemic episodes. While Nishida et al. emphasize the clinical significance of coordination deficiencies as predictors of cerebrovascular risk, our study examines their frequency in the general population [61].

Table 31:  Individual No. of responses for Test 11

S. No

Skew Deviation Test

No. of Participants

Percentage (%)

Mean ± SD

1

2

3

4

5

6

Bilateral

Bilateral>Left

Bilateral>Right

Left

Right

Normal

33

0

1

233

195

56

6.37%

0

0.19%

44.98%

37.64%

10.81%

 

 

4.40±1.10.

Our study of 518 participants found a high prevalence of skew deviation, with 44.98% showing left eye involvement, 37.64% right eye involvement, 10.81% normal alignment, and 6.37% with moderate deviation. Compared to M. Chandrakumar et al.'s findings on posture-related changes that aid in diagnosis, and Wong's emphasis on clinical differentiation, our data adds valuable prevalence insight to the overall understanding of skew deviation. [62].

CONCLUSION

Given the high prevalence of vertigo among young adults in the Amaravati Capital Region and the importance of early diagnosis and comprehensive management, this study's findings provide a solid basis for future research focusing on targeted prevention, timely intervention, and effective therapeutic strategies to reduce the burden of vertigo in this population. Clinical evaluations identified key risk factors, such as lifestyle and environmental influences, and revealed multiple underlying causes.

ABBREVIATIONS

BPPV: benign paroxysmal positional vertigo; SSCDS: superior semicircular canal dehiscence syndrome; HINTS: Head impulse, nystagmus, test of skew; VOR: vestibulo-ocular reflex; SCCs: semicircular canals; DVA: Dynamic visual acuity; HIT: Head Impulse Test; OTR: Ocular Tilt Reaction; SVV: Subjective Visual Vertical; SD: skew deviation; VN: vestibular neuritis; SVN: superior vestibular nerve; SSRIs: selective serotonin reuptake inhibitors; VM: vestibular migraine; HRV: heart rate variability; VDB: vertigo dizziness, and balance disorders;

ACKNOWLEDGEMENTS

We gratefully acknowledge our guide, Mr. Sreenu Thalla Associate Professor, Department of Pharmacology, Vignan Pharmacy College and Dr. P. Srinivasa Babu, Principal of Vignan Pharmacy College, Vadlamudi for ultimate support.

REFERENCES

1.    Stanton M, Freeman AM. Vertigo. [Updated 2023 Mar 13]. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www. ncbi.nlm.nih.gov/books/NBK482356/

2.    Ahmad JG, Lin KF. Ménière's disease is a disorder of the inner ear. Curr Opin Otolaryngol Head Neck Surg. 2023 Oct 1;31(5):320-324. https://doi.org/10.1097/moo.0000000000000921

3.    Mohseni-Dargah M, Falahati Z, Pastras C, Khajeh K, Mukherjee P, Razmjou A, Stefani S, Asadnia M. Meniere's disease: Pathogenesis, treatments, and emerging approaches for an idiopathic bioenvironmental disorder. Environ Res. 2023 Dec 1;238(Pt 1):116972. https://doi.org/10.1016/j.envres.2023.116972Epub 2023 Aug 28. PMID: 37648189.

4.    Hornibrook J, Bird P. a New Theory for Ménière's Disease: Detached Saccular Otoconia. Otolaryngol                                      Head Neck Surg.               2017Feb;156(2):350-352. https://doi.org/10.1177/0194599816675843, Epub 2016     Nov 14 PMID: 28145833.

5.    Vertigo-associated disorders: MedlinePlus Medical Encyclopedia

6.    https://www.starhealth.in/blog/central-vertigo/

7.    Motawea KR, Monib FA, Shaheen N. Acute Vertigo in a Patient Following COVID- 19 Infection: A Case Report and Literature Review. Indian J Otolaryngol Head Neck Surg. 2023 Apr 20;75(3):1-5. https://doi.org/10.1007/s12070-023-03745-x . Epub ahead of print. PMID: 37362121; PMCID: PMC10116458.

8.    Garaycochea O, Pérez-Fernández N. Variants of posterior semicircular canal involvement in benign paroxysmal positional vertigo. ActaOtorrinolaringolEsp (Engl Ed). 2024 Sep-Oct;75(5):324-334. https://doi.org/10.1016/j.otoeng.2024.01.013Epub 2024 Mar 2. PMID: 38438080.

9.    Ren YY, Wang YJ, Li JL, Liu M, Xia F. Low vitamin D and uric acid status in patients with benign paroxysmal positional vertigo. SciProg. 2023 Oct- Dec;106(4):368504231205397. https://doi.org/10.1177/00368504231205397 PMID: 37807761; PMCID: PMC10563478.

10.     Koukoulithras I, Drousia G, Kolokotsios S, Plexousakis M, Stamouli A, Roussos C, Xanthi E. A Holistic Approach to a Dizzy Patient: A Practical Update. Cureus. 2022 Aug 4;14(8): e27681. https://doi.org/10.7759/cureus.27681 . PMID: 36106247; PMCID: PMC9447938.

11.     Kirovakov Z, Kutsarov A, Todorov S, Penchev P. Vertigo During Pregnancy: A Narrative Review of the Etiology, Pathophysiology, and Treatment. Cureus. 2024 Mar 6;16(3): e55657. https://doi.org/10.7759/cureus.55657 . PMID: 38495964; PMCID: PMC10944550.

12.     Thompson TL, Amedee R. Vertigo: a review of common peripheral and central vestibular disorders. Ochsner J. 2009 Spring;9(1):20-6. PMID: 21603405; PMCID:

13.     https://pmc.ncbi.nlm.nih.gov/articles/PMC3096243/ .

14.     Vishal Paresh Shah MD, MPH, Lucas Oliveira J. e Silva MD, MS, Wigdan Farah MBBS, Mohamed O. Seisa MD, Abdalla Kara Balla MD, April Christensen MD, Magdoleen Farah MBBS, Bashar Hasan MD, Fernanda Bellolio MD, MS, M. Hassan Murad MD, MPH. First published: 01 December 2022 doi: https://doi.org/10.1111/acem.14630

15.     Kim, Ji-Soo et al. ‘Vascular Vertigo and Dizziness: Diagnostic Criteria’. 1 Jan. 2022: 205 – 222.doi ; https://doi.org/10.1111/acem.14630

16.     Chen, J., Zhang, S., Cui, K. et al. Risk factors for benign paroxysmal positional vertigo recurrence: a systematic review and meta-analysis. J Neurol 268, 4117–4127 (2021). https://doi.org/10.1007/s00415-020-10175-0

17.     Koukoulithras I, Drousia G, Kolokotsios S, et al. (August 04, 2022) A Holistic Approach to a Dizzy Patient: A Practical Update. Cureus 14(8): e27681. doi:https://public.cureus.com/article-show-redesign/doi-icon.png

18.     Thompson TL, Amedee R. Vertigo: a review of common peripheral and central vestibular disorders. Ochsner J. 2009 Spring;9(1):20-6. PMID: 21603405; PMCID: PMC3096243.doi: https://pubmed.ncbi.nlm.nih.gov/21603405/

19.     Cao W, Geng Y, Chang J, Li F. Risk factors for benign paroxysmal positional vertigo and construction of a nomogram predictive model. Am J Transl Res. 2024 Jun 15;16(6):2435-2444. doihttps://pubmed.ncbi.nlm.nih.gov/39006265/ . PMID: 39006265; PMCID: PMC11236668.

20.     Filippopulos FM, Albers L, Straube A, Gerstl L, Blum B, Langhagen T, et al. (2017) Vertigo and dizziness in adolescents: Risk factors and their population attributable risk. PLoS ONE 12 (11): e0187819. https://doi.org/10.1371/journal.pone.0187819

21.     Salah M, Van de Heyning P, De Hertogh W, Van Rompaey V, Vereeck L. Clinical balance testing to screen for patients with vestibular disorders: a retrospective case- control study. Otology & Neurotology. 2020 Oct 1;41(9):1258-65. https://doi.org/10.1097/MAO.0000000000002757

22.     Hedetoft M, Hyldegaard O. Postural stability in patients with decompression sickness evaluated by means of Quantitative Romberg testing. Undersea & Hyperbaric Medicine. 2015 Sep 1;42(5). https://pubmed.ncbi.nlm.nih.gov/26591978/

23.     Kitsko, D. J., &Dohar, J. E. (2007). Inner ear and facial nerve complications of acute otitis media, including vertigo. Current Allergy and Asthma Reports, 7(6), 444–450. doi: https://doi.org/10.1007/s11882-007-0068-1

24.     Harker LA, Pignatari SS: Facial nerve paralysis secondary to chronic otitis media without cholesteatoma. Am J Otol 1992, 13:372–374. https://pubmed.ncbi.nlm.nih.gov/1415504/

25.     Yetiser S, Tosun F, Kazkayasi M: Facial nerve paralysis due to chronic otitis media. OtolNeurotol 2002, 23:580–588. https://doi.org/10.1097/00129492-200207000-00030

26.     Altuntas A, Unal A, Aslan A, et al.: Facial nerve paralysis in chronic serous otitis media: Ankara Numune Hospital experience. AurisNasis Larynx 1998, 25:169–172. https://doi.org/10.1016/s0385-8146(98)00002-9

27.     Paparella MM, Goycoolea MV, Meyerhoff WL: Inner ear pathology and otitis media: a review. Ann OtolRhinolLaryngolSuppl 1980, 89:249–253. https://doi.org/10.1177/00034894800890s358

28.     Juselius H, Kaltiokallio K: Complications of acute and chronic otitis media in the antibiotic era. ActaOtolaryngol (Stockh) 1972, 74:445–450 https://doi.org/10.3109/00016487209128475

29.     Hyden D, Akerlind B, Peebo M: Inner ear and facial nerve complications of acute otitis media with focus on bacteriology and virology. ActaOtolaryngol 2006, 126:460–466. https://doi.org/10.1080/00016480500401043

30.     Sun AH, Parnes LS, Freeman DJ: Comparative perilymph permeability of cephalosporins and its significance in the treatment and prevention of suppurativelabyrinthitis. Ann OtolRhinolLaryngol 1996, 105:54–57. https://doi.org/10.1177/000348949610500109

31.     De Stefano A, Dispenza F, Suarez H, Perez-Fernandez N, Manrique-Huarte R, Ban JH, Kim MB, Strupp M, Feil K, Oliveira CA, Sampaio AL. A multicenter observational study on the role of comorbidities in the recurrent episodes of benign paroxysmal positional vertigo. Aurisnasus larynx. 2014 Feb 1;41(1):31-6.   https://www.sciencedirect.com/science/article/abs/pii/S0385814613001557

32.     Ogun OA, Janky KL, Cohn ES, Büki B, Lundberg YW. Gender-based comorbidity in benign   paroxysmal      positional         vertigo.            PloS     one.     2014    Sep 4;9(9):e105546. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0105546

33.     Feder RE. Transdermal scopolamine withdrawal syndrome. ClinNeuropharmacol. 1999 Mar-Apr;22(2):120.   PMID: 10202610.       https://doi.org/10.1097/00002826-199903000-00011

34.     Takeda N, Morita M, Hasegawa S, Kubo T, Matsunaga T. Neurochemical mechanisms of motion sickness. Am J Otolaryngol. 1989 Sep-Oct;10(5):351-9. doi: 10.1016/0196- 0709(89)90112-9. PMID: 2573285. https://doi.org/10.1016/0196-0709(89)90112-9

35.     Blair SM, Gavin M. Modifications of vestibulo-ocular reflex induced by diazepam: experiments in the macaque. Arch Otolaryngol. 1979 Dec;105(12):698-701. doi: 10.1001/archotol.1979.00790240012003.   PMID: 116638. https://doi.org/10.1001/archotol.1979.00790240012003

36.     Hackenberg B, O'Brien K, Döge J, Lackner KJ, Beutel ME, Münzel T, Wild PS, Pfeiffer N, Chalabi J, Matthias C, Bahr-Hamm K. Vertigo and its burden of Disease- Results from a population-based cohort study. Laryngoscope Investig Otolaryngol. 2023 Oct 23;8(6):1624-1630. https://doi.org/10.1002/lio2.1169

37.     Sreenivas V, Sima NH, Philip S. The Role of Comorbidities in Benign Paroxysmal Positional Vertigo. Ear, Nose & Throat Journal. 2021;100(5):NP225-NP230. https://doi.org/10.1177/0145561319878546

38.     Migraine-Associated Vertigo Cherchi, Marcello et al. Otolaryngologic Clinics of North America, Volume 44, Issue 2, 367 – 375https://doi.org/10.1016/j.otc.2011.01.008

39.     Katzenberger B, Koller D, Strobl R, Kisch R, Sanftenberg L, Voigt K, Grill E. Exposure to anticholinergic and sedative medication is associated with impaired functioning in older people with vertigo, dizziness and balance Disorders-Results from the longitudinal multicenter study MobilE-TRA. Front Pharmacol. 2023 Mar 3; 14:1136757. https://doi.org/10.3389/fphar.2023.1136757

40.     von Brevern M, Radtke A, Lezius F, Feldmann M, Ziese T, Lempert T, Neuhauser H. Epidemiology of benign paroxysmal positional vertigo: a population-based study. J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):710-5. https://doi.org/10.1136/jnnp.2006.100420

41.     Casani, A.P.; Gufoni, M.; Ducci, N. Episodic Vertigo: A Narrative Review Based on a Single-Center Clinical Experience. Audiol. Res. 2023, 13, 845-858.https://doi.org/10.20944/preprints202309. 0479.v1

42.     Teggi R, Caldirola D, Colombo B, et al. Dizziness, migrainous vertigo and psychiatric disorders. The Journal of Laryngology & Otology. 2010;124(3):285-290. doi: https://doi.org/10.1017/s0022215109991976

43.     Li W, Cheng Y, Ma Q, Wu Z, Wang Z. Clinical characteristics and treatment outcomes of patients with insulinoma-a single center's experience of 76 cases over a 10-year period. Heliyon. 2025 an10;11(2):e41799.doi:https://doi.org/10.1016/j.heliyon 2025.e41799

44.     Nowaczewska, M., Wiciński, M., Straburzyński, M., & Kaźmierczak, W. (2020). The Prevalence of Different Types of Headache in Patients with Subjective Tinnitus and Its Influence on Tinnitus Parameters: A Prospective Clinical Study. Brain Sciences, 10(11), 776. https://doi.org/10.3390/brainsci10110776

45.     Xiao BJ, Bi Y, Zheng TH. [investigation on the triggers and the effect of healthy education on recurrence of vestibular migraine]. Lin Chuang er bi yan hou tou Jing wai ke za zhi = Journal of Clinical Otorhinolaryngology Head and Neck Surgery. 2019 Jul;33(7):577-580. https://doi.org/10.13201/j.issn.1001-1781.2019.07.001

46.     Ichijo, H. (2016). Onset time of benign paroxysmal positional vertigo. Acta Oto- Laryngologica, 137(2), 144–148 https://doi.org/10.1080/00016489.2016.1221130

47.     Gunes-Bayir, A., Tandogan, Z., Gedik-Toker, Ö., Yabaci-Tak, A., & Dadak, A. (2023). A Comparison Study of Nutritional Assessment, Diet and Physical Activity Habits, Lifestyle and Socio-Demographic Characteristics in Individuals with and without Dizziness/Vertigo. Nutrients, 15(18), 4055. https://doi.org/10.3390/nu15184055

48.     Grill, E., Strupp, M., Müller, M. et al. Health services utilization of patients with vertigo in primary care: a retrospective cohort study. J Neurol 261, 1492–1498 (2014). https://doi.org/10.1007/s00415-014-7367-y

49.     Hall CD, Herdman SJ, Whitney SL, Anson ER, Carender WJ, Hoppes CW, Cass SP, Christy JB, Cohen HS, Fife TD, Furman JM, Shepard NT, Clendaniel RA, Dishman JD, Goebel JA, Meldrum D, Ryan C, Wallace RL, Woodward NJ. Vestibular Rehabilitation for Peripheral Vestibular Hypofunction: An Updated Clinical Practice Guideline from the Academy of Neurologic Physical Therapy of the American Physical Therapy  Association.  J  Neurol  Phys  Ther. 2022  Apr  1;46(2):118-177.https://doi.org/10.1097/npt.0000000000000382

50.     de Joode, L.E.G.H., Martin, E.C., Stultiens, J.J.A. et al. The DizzyQuest: to have or not to have… a vertigo attack? J Neurol 267 (Suppl 1), 15–23 (2020). https://doi.org/10.1007/s00415-020-10043-x

51.     Çakır S, Sahin A, Gedik-Soyuyuce O, Gence Gumus Z, Sertdemir İ, Korkut N, Yalınay Dikmen P. Assessing the impact of migraine on benign paroxysmal positional vertigo symptoms and recovery. BMC Neurol. 2024 May 2;24(1):148 https://doi.org/10.1186/s12883-024-03606-2 . PMID: 38698310; PMCID: PMC11064330

52.     Schmid, D.A., Allum, J.H.J., Sleptsova, M. et al. Relation of anxiety and other psychometric measures, balance deficits, impaired quality of life, and perceived state of health to dizziness handicap inventory scores for patients with dizziness. Health Qual Life Outcomes 18, 204 (2020). https://doi.org/10.1186/s12955-020-01445-6

53.     Ori, M., Arra, G., Caricato, M., Freccia, R., Frati, F., De Bonis, T., Ricci, G., & Faralli, M. (2020). Age-related features in vestibular migraine onset: A multiparametric analysis. Cephalalgia: an international journal of headache, 40(14), 1605–1613. Ori, M., Arra, G., Caricato, M., Freccia, R., Frati, F., De Bonis, T., Ricci, G., & Faralli, M. (2020). Age-related features in vestibular migraine onset: A multiparametric analysis. Cephalalgia: an international journal of headache, 40(14), 1605–1613.. https://doi.org/10.1177/0333102420951505

54.     Baday-Keskin, D., Taş, M. B., & Bayar-Muluk, N. (2025). Factors Associated with Balance and Fear of Falling in Patients with Benign Paroxysmal Positional Vertigo: A Controlled Cross-Sectional Study. Clinical otolaryngology: official journal of ENT- UK; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico- Facial Surgery, Advance online publication. https://doi.org/10.1111/coa.14281

55.     Gunlu S, Aktan A. Evaluation of the heart rate variability in cardiogenic vertigo patients. Int J Cardiovasc Acad. 2022 Jul 1;8(3):73. https://ijcva.org/pdf/1fe4afca-adad- 4137-be7c-36a5e5ab6910/articles/ijca.ijca_13_22/ijca-8-73-En.pdf

56.     Kim, Moon-Jung, and Guil Rhim. 2023. "Blood Pressure Response to the Head-Up Tilt Test in Benign Paroxysmal Positional Vertigo" Journal of Clinical Medicine 12, no. 24: 7725. Kim, Moon-Jung, and Guil Rhim. 2023. "Blood Pressure Response to the Head- Up Tilt Test in Benign Paroxysmal Positional Vertigo" Journal of ClinicalMedicine 12, no. 24: 7725. https://doi.org/10.3390/jcm12247725

57.     Eza-Nuñez P, Fariñas-Alvarez C, Perez-Fernandez N. The caloric test and the video head-impulse test in patients with vertigo. The journal of international advanced otology. 2014 May 1;10(2):144. DOI: https://advancedotology.org/content/files/sayilar/83/buyuk/144-149.pdf

58.     Verghese J, Ambrose AF, Lipton RB, Wang C. Neurological gait abnormalities and risk of falls in older adults. J Neurol. 2010 Mar;257(3):392-8. doi: https://doi.org/10.1007/s00415-009-5332-y

59.     Rajamani, Santhosh Kumar, Radha Srinivasan Iyer, and Anusha Venkatraman. 2024. "Comparison of Halmágyi–Curthoys Head Impulse (Thrust) Test with Romberg’s Test in Detection of Vestibular Hypofunctioning in Vertigo Patients" Journal of Otorhinolaryngology, Hearing and Balance Medicine 5, no. 1: 4. https://doi.org/10.3390/ohbm5010004

60.     Bech MW, Staffe AT, Hougaard DD. A mechanical rotation chair provides superior diagnostics of benign paroxysmal positional vertigo. Front Neurol. 2023 Jan 27; 14:1040701. doi: https://doi.org/10.3389/fneur.2023.1040701

61.     Nishida K, Usami T, Matsumoto N, Nishikimi M, Takahashi K, Matsui S. The finger- to-nose test improved diagnosis of cerebrovascular events in patients presenting with isolated dizziness in the emergency department. Nagoya J Med Sci. 2022 Aug;84(3):621-629. https://doi.org/10.18999/nagjms.84.3.621

62.     M. Chandrakumar, HBSc, A. Blakeman, H.C. Goltz, PhD, J.A. Sharpe, MD, FRCPC, and A.M.F. Wong, MD, PhD, FRCSC August 16, 2011 issue77 (7) 638-644 doi: https://doi.org/10.1212/WNL.0b013e3182299f71

 



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